Microbios, Inc.

Other

Matthew Ryan Garner

Joseph F Flint

Mark Dominis Holt

-based probiotic compositions for inclusion in microbial-based products. In one instance, the microbial-based product takes the form of an animal feed additive. When used as a feed additive for animals, especially ruminants, and in particular cattle, the following benefits from the composition are noted: (i) improved milk yield in dairy cattle, (ii) improved milk composition in dairy cattle, (iii) increased weight gain-to-feed intake ratio in beef cattle (feed efficiency), and (vi) improved average daily weight gain. Bothstrains MB101 having ATCC Accession Number PTA-121710 and MB102 having ATCC Accession Number PTA-121711 are particularly effective at producing these results. Another marked benefit of the compositions when used as an animal feed additive is inhibition of pathogenic growth includingand

Composition for enhanced milk production and feed efficiency and pathogen inhibition

A probiotic, useable as a feed additive, particularly for animals, that includes live, viable beneficial bacteria strains. Because the beneficial bacteria are alive, the probiotic has a capacity to kill and inhibit the growth of pathogens such asand. In certain select combinations, the probiotic bacteria have shown a greater than 93% reduction inand a greater than 97% reduction in. Among other realized beneficial effects of the probiotics such as improved feed efficiency, increased milk production and enhanced pregnancy rates, pathogen inhibition has been observed in beef cattle and dairy cattle, as well as their calves. Probiotic mixtures variously containing MB101 and/or MB102have shown consistentandinhibition rates approaching 100%.

Probiotic composition and feed additive

Processes that produce microorganisms that can be incorporated into microbial-based products that result in high viable cell yields and shelf-stable products. Among other things, these microbial-based products inhibit pathogenic growth. In one application, the microbial-based products take the form of a supplement. In another application, the microbial-based products take the form of a food additive. When used as a supplement or food additive for animals, and in particular for cattle, the following benefits are noted: (i) increased weight gain-to-feed intake ratio (feed efficiency), (ii) improved average daily weight gain, (iii) improved milk yield, and (vi) improved milk composition by dairy cows. Bothstrains MB101 having ATCC Accession Number PTA-121710 and MB102 having ATCC Accession Number PTA-121711 are particularly affective at producing these results, and the effects of which can be enhanced by

Lactobacillus-basedinhibition

A bacterial composition and method that inhibitsO157:H7 growth by as much as 93% andgrowth by as much as 97%, together with commensurate inhibition rates against the Big-Sixstrains referred to as the non-O157 STECs that includeO121:H19;O45:H2;O103:H11;O145,O26:H11; andO111. The composition is constituted of various combinations of the following unique pathogen-inhibiting bacteria: (1); (2)(3)

Probiotic pathogen inhibition composition and method

Processes to produce microorganisms that can be incorporated into a microbial-based product that results in high viable cell yields and shelf-stable products are disclosed. These microbial-based products are useful for inhibiting pathogenic growth and as a food additive. A preferred microorganism is a lactic acid producing bacteria. In one embodiment, the process comprises inoculating either a fermentation medium withorbacterial cells, harvesting theorbacterial cells at least partially during the log phases, concentrating the bacterial cells, and preserving the bacterial cells at a concentration of at least 5&#xd7;10cfu/ml.

Process for the manufacture of pathogen inhibiting bacteria

Processes to produce microorganisms that can be incorporated into a microbial-based product that results in high viable cell yields and shelf-stable products are disclosed. These microbial-based products are useful for inhibiting pathogenic growth and as a food additive. A preferred microorganism is a lactic acid producing bacteria. In one embodiment, the process comprises inoculating afermentation medium with lactic acid producing bacterial cells, harvesting the lactic acid producing bacterial cells at least partially during the log phases, concentrating the lactic acid producing bacterial cells, and preserving the lactic acid producing bacterial cells at a concentration of at least 5&#xd7;10cfu/ml.

Processes to produce microorganisms that can be incorporated into a microbial-based product that results in high viable cell yields and shelf-stable products are disclosed. These microbial-based products are useful for inhibiting pathogenic growth and as a food additive. A preferred microorganism is a lactic acid producing bacteria. In one embodiment, the process comprises inoculating a lactobacillus fermentation medium with lactic acid producing bacterial cells, harvesting the lactic acid producing bacterial cells at mid to late log phase, concentrating the lactic acid producing bacterial cells, and preserving the lactic acid producing bacterial cells at a concentration of at least 5&#xd7;10cfu/ml.

Process and composition for manufacture of a microbial-based product

A dairy administered animal feed additive that promotes animal health and growth, reduces mortality and can act as an antibiotic substitute. The additive inhibits pathogen growth resulting in lower pathogen load within the animal and reduced pathogen sheading to the environment. The additive includes bacteria that inhibitO157:H7 growth by as much as 93% andgrowth by as much as 97%, together with commensurate inhibition rates against the Big-Sixstrains. The additive includes various combinations of the following pathogen-inhibiting bacteria:; and

Dairy administered bacterial composition

A juvenile animal feed additive, such as for calves, that promotes animal health and growth, reduces mortality and can act as an antibiotic substitute. The additive inhibits pathogen growth resulting in lower pathogen load within the animal and reduced pathogen sheading to the environment. The additive includes bacteria that inhibitO157:H7 growth by as much as 93% andgrowth by as much as 97%, together with commensurate inhibition rates against the Big-Sixstrains. The additive includes various combinations of the following pathogen-inhibiting bacteria:; and

Calf administered bacterial composition

Composition including a pathogen inhibiting bacterial probiotic and a fructooligosaccharide (FOS) prebiotic particularly suited as a feed additive administered to juvenile animals such as calves that promotes animal health and growth, reduces scours and mortality, and can act as an antibiotic substitute. The additive inhibits pathogen growth resulting in lower pathogen load within the animal and pathogen sheading. The prebiotic-probiotic additive includes bacteria that inhibitO157:H7 growth by as much as 93% andgrowth by as much as 97%, as well as the Big-Sixstrains. The probiotic is constituted of various combinations of four pathogen-inhibiting bacteria:; and

FOS-based prebiotic and bacterial-based probiotic

A feedlot administered animal feed additive that promotes animal health and growth, reduces mortality and can act as an antibiotic substitute. The additive inhibits pathogen growth resulting in lower pathogen load within the animal and reduced pathogen sheading to the environment. The additive includes bacteria that inhibitO157:H7 growth by as much as 93% andgrowth by as much as 97%, together with commensurate inhibition rates against the Big-Sixstrains. The additive includes various combinations of the following pathogen-inhibiting bacteria:; and

Feedlot administered bacterial composition

Methods to reduce or inhibit populations of pathogenic bacteria in animals are disclosed. These methods include providing a number of administrations of probiotic microorganism compositions containing one or more strains or species of probiotic microorganisms. Routes of administration, dosage of administration and pathogenic organisms to be reduced or inhibited are also disclosed.

Microbial product containing multiple microorganisms

Composition and method for processing prolamin-containing feed source into a low-vitreous gelatinous feedstuff. The feedstuff is fed to ruminant animals for the purpose of potentiating either milk production and/or conception. The feed source can be corn and the ruminant animal can be a bovine, and might be a cow. The method includes processing, by extrusion, a prolamin-containing feed source having a starch-protein matrix within which the included protein is composed of at least 3% percent prolamin. This processing produces a hydrophilic gelatinous feedstuff that has starch and protein content. The hydrophilic low-vitreous gelatinous feedstuff is fed to a ruminant animal. A rumen-retained portion of the fed feedstuff is retained within the rumen of the animal for at least a twenty-four hour period, and during the first twenty-four hours of that period, at least seventy-five percent of the starch content of the rumen-retained portion of the fed feedstuff is digested.

Method for processing prolamin-containing feed for a ruminant animal to potentiate milk production or conception

A bacterial composition that inhibitsO157:H7 growth by as much as 93% andgrowth by as much as 97%, together with commensurate inhibition rates against the Big-Sixstrains referred to as the non-O157 STECs that includeO121:H19;O45:H2;O103:H11;O145,O26:H11; andO111. The composition is constituted of various combinations of the following four unique pathogen-inhibiting bacteria: (1)strain MB101; (2)strain MB102; (3)strain MB505; and (4)strain MB902. Each of the discovered bacteria is deposited with the American Type Culture Collection (ATCC) and respectively has an individual ATCC Accession Number.

Bacterial composition

Processes to produce microorganisms that can be incorporated into a microbial-based product that results in high viable cell yields and shelf-stable products are disclosed. These microbial-based products are useful for inhibiting pathogenic growth and as a food additive. A preferred microorganism is a lactic acid producing bacteria. In one embodiment, the process comprises inoculating afermentation medium with lactic acid producing bacterial cells, harvesting the lactic acid producing bacterial cells at mid to late log phase, concentrating the lactic acid producing bacterial cells, and preserving the lactic acid producing bacterial cells at a concentration of at least 5&#xd7;10cfu/ml.

Growing community of inventors

Amarillo, TX, United States of America

Matthew Ryan Garner