University of Virginia Patent Foundation

University of California

Matthew R Begley

James P Landers

Jerome Ferrance

Michael H Jones

Christopher J Easley

Marcel Utz

James M Karlinsey

Tyler Ray

Dan Leslie

Jennifer Monahan-Dian

Rachel Collino

George T Gillies

William C Broaddus

Daniel C Leslie

John A Jane

Ling Huang

Scott Barker

A method of three-dimensional (3D) printing includes applying a solution to a channel. The solution includes a plurality of anisotropic particles suspending in the solution. Acoustic waves are applied to the channel. The frequency of the acoustic waves is configured to organize the plurality of anisotropic particles into one or more columns of organized anisotropic particles. The channel is connected to a printhead and a waste outlet. The solution comprising the one or more columns of organized anisotropic particles is deposited on a substrate via the printhead outlet.

Three-dimensional (3D) printing methods using acoustic waves and anisotropic particles

A three-dimensional (3D) printer includes an acoustophoresis device having at least a first inlet, a first outlet, and a channel defined between the first inlet and the first outlet. A piezoelectric device is adhered to a surface of the acoustophoresis device to generate sound waves within the channel. A printhead is connected to the first outlet of the acoustophoresis device, wherein a solution comprising anisotropic particles is delivered to the at least first inlet and wherein the anisotropic particles are organized into one or more columns along an axis parallel to a direction of flow of the solution by standing acoustic waves generated by the piezoelectric device, wherein the at least one column of anisotropic particles is aligned with the first outlet, and wherein the first outlet is in fluid communication with the printhead to deliver one or more columns of ordered, anisotropic particles to the printhead.

System for three-dimensional (3D) printing with piezoelectric device

A mechanical input to a fluidic filter network can be actuated. The fluidic filter network can include respective branches fluidically coupling the mechanical input to respective deformable mechanical outputs. A mechanical displacement can be selectively coupled a selected deformable mechanical output of the fluidic filter network to a deformable mechanical input of a microfluidic device. A fluid flow in a portion of the microfluidic device can be controlled using the displacement, the selected deformable mechanical output can be selected at least in part by actuating the mechanical input to produce a displacement having energy in a specified range of frequencies, and the fluidic filter network is generally fluidically isolated from the microfluidic device.

Frequency-based filtering of mechanical actuation using fluidic device

Systems and methods for use in monitoring treatment of pressure-related conditions, such as hydrocephalus, include an implantable vessel, and a meter including one or more microfluidic channels connected to the vessel. The microfluidic channels may be configured to detect at least one of pressure and fluid flow rate through the vessel and to be read out remotely by a wirelessly coupled external device. The meter may include a passive resonant (LC) circuit. A dynamic flap may be included in the microfluidic channel that may act as part of the LC circuit. An external device may also be configured to inductively couple remotely to the LC circuit, with-out physical connections to the implantable vessel or pressure meter, and to display a pressure acting on the pressure meter and/or a fluid flow through the meter.

Meters for in-vivo monitoring

The present invention relates to microfluidic systems and methods for controlling the flow of fluid using passive components engineered into the microchannels. These passive flow components include fluidic diodes, fluidic capacitors, and fluidic inductors. Various fluidic circuits are provided to control fluid flow including fluid rectifiers, fluid band pass filters, and fluid timers.

Passive components for micro-fluidic flow profile shaping and related method thereof

In an example, an apparatus, such as a microfluidic assembly, can include or can include using a channel including a valve seat, a valve film configured to adjust position with respect to the valve seat, and a first electrode configured to actuate the valve film electrostatically to adjust the position of the valve film to control a flow of a fluid in the channel laterally across the valve seat, the flow in a direction substantially parallel to the film.

Electrostatic actuation for management of flow in micro-total analysis systems (&#x3bc;-TAS) and related method thereof

The invention relates to sensors for detecting chemical and biological material and for chemical actuation. In particular, the sensors of the present invention incorporates membranes or beams that are deformable in the presence of chemical adsorption on its surface. The sensor of the present invention contains a polymeric membrane or beam () that is clamped at least at two opposing ends () and ().

Microdevices for chemical sensing and chemical actuation

The present invention relates to microfluidic devices, and in particular, flow management in such devices. In particular, the present invention provides an electrostatic valve for flow manipulation in a microfluidic device. The valve of the present invention sits on a valve seat in a microchannel and deflects away from the valve seat by electrostatic actuation to assume an opened configuration to allow fluid flow.

Growing community of inventors

Charlottesville, VA, United States of America

Matthew R Begley