Allosource

Matthew Peterson

Adrian C Samaniego

Reginald L Stilwell

Matthew Southard

Kenneth Blood

Jan Zajdowicz

Robert L Bundy

Timothy Bennett

Cathleen Lucine Badillo

Bruce Mock

Lauren Blume

Yurid Gourgel

Luke Shubin

Joslynn Shamis

Aidan Griffin

Nate Henriod

Arthur Joslyn

Kathryn Hanzlicek

Marina Katelyn Bull

Matthew James Southard

Systems and methods for the automated demineralization of bone and decellularization of soft tissue include a mixing assembly communicatively coupled with a control and reporting system. The mixing assembly includes a housing that supports a cannister sub-assembly forming a mixing chamber having a reagent inlet, a reagent outlet, and an internal fluid agitator. A motor is operably coupled with the agitator and configured to spin the agitator in first and second directions relative to the cannister, thereby agitating fluid contained within the mixing chamber. At least one pump is configured to progressively inject measured quantities of a plurality of reagents into the mixing chamber. The associated control and reporting system includes a user terminal that displays a graphical user interface enabling a user to initiate an automated demineralization or decellularization procedure in which the mixing assembly demineralizes tissue placed within the mixing chamber. Other embodiments are also disclosed.

Automated system and methods for tissue demineralization

Embodiments of the present invention encompass graft assemblies, and methods for their use and manufacture. An exemplary bone graft assembly includes first and second bone pieces having respective mating features which, when combined, define non-uniform press fit. Related embodiments encompass graft assemblies having enclosed or hidden mating features.

Multi-piece machine graft systems and methods

Growing community of inventors

Thornton, CO, United States of America

Matthew Peterson