Bryn Pharma, LLC

Meridian Medical Technologies, Inc.

Matthew P Robben

Steven Hartman

Michelle Lobel

Michael Mesa

Kenneth L Dretchen

Robert L Hill

Steven M Griffiths

Provided herein are epinephrine spray formulations. Also provided herein are methods of treating anaphylaxis by administering epinephrine spray formulations to subjects in need of such treatment.

Epinephrine spray formulations

Provided herein are epinephrine spray formulations and methods of administering the same. Also provided herein are methods of treating anaphylaxis by administering epinephrine spray formulations to subjects in need of such treatment. The spray formulations contain epinephrine or a pharmaceutically acceptable salt thereof, one or more of an antioxidant, an antimicrobial preservative, an isotonicity agent, an absorption enhancer, a viscosity modifier, and/or a buffering agent.

An automatic injector separately stores liquid and dry components in respective compartments. When the injector is activated, a fluid-directing member between the liquid and dry compartments causes the liquid component to form a vortex as the liquid flows into the dry compartment. This allows the two components to combine more thoroughly and quickly to form a liquid solution that is delivered to an injection site.

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Pittsford, NY, United States of America

Matthew P Robben