Scimed Life Systems, Inc.

Anulex Technologies, Inc.

Osprey Medical, Inc.

Cvrx, Inc.

Krt Investors, Inc.

Scimed Lift Systems, Inc.

Scimed Technology, Inc.

Matthew M Burns

Rodney L Houfburg

Lawrence William Wales

Joseph C Cauthen, Iii

Bradley John Wessman

Brian Lee Dukart

Ishmael Bentley

Paul H Burmeister

Todd J Mortier

David Martin Kaye

Tuan Minh Doan

Thomas R Hektner

Daniel O Adams

Robert S Kieval

Daniel R Mans

Daniel M Lafontaine

David J Serdar

David W Lodin

Peter Trexler Keith

Cyril J Schweich, Jr

Kent David Harrison

Charles L Euteneuer

Chad John Kugler

Scott Raymond Smith

Martin A Rossing

Bruce J Persson

Richard G Cornelius

Michelle M Arney

Eric D Irwin

Joseph D Farrell

Joseph C Cauthen Iii

Gina L Hansen

Joseph C Iii Cauthen

Joseph Iii Cauthen

Bradley J Wessmann

A system for modulating delivery of a fluid medium includes an injector for injecting the fluid medium during an injection cycle, a delivery catheter including a conduit for delivering the fluid medium, a manifold disposed in a fluid medium flow path between the injector and the delivery catheter, and a pulsatile generator. The pulsatile generator is configured to apply a pulsatile force to the fluid medium defined by a plurality of duty cycles during the injection cycle, each of the duty cycles including a first pressure level and a second pressure level that is lower than the first pressure level.

Adjustable medium diverter

Devices, systems and methods for controlling, regulating, altering, transforming or otherwise modulating the delivery of a substance to a delivery site. The devices, systems and methods optimize the delivery of the substance to an intended site, such as a vessel, vascular bed, organ and/or other corporeal structures, while reducing inadvertent introduction or reflux substance to other vessels, vascular beds, organs, and/or other structures, including systemic introduction.

Devices and methods for modulating medium delivery

Systems and methods for modulating delivery of a fluid medium to a selected site within a patient's body are described. A system includes a syringe for injecting the fluid medium, a delivery catheter including a conduit for delivering the fluid medium from outside of the body to the selected site within the body, a diversion reservoir configured to receive a portion of the fluid medium, and a flow diverter assembly disposed in a fluid medium flow path between the syringe and the delivery catheter. The flow diverter assembly is configured to divert the portion of the fluid medium from the chamber of the syringe away from the delivery of the medium through the delivery catheter conduit during injecting with the syringe. The flow diverter assembly simultaneously increases fluid medium flow resistance with increasing pressure level of the fluid medium passing into the flow diverter assembly.

A system for modulating delivery of a fluid medium to a selected site within a patient's body includes a syringe for injecting the fluid medium, a delivery catheter including a conduit for delivering the fluid medium from outside of the body to the selected site within the body, a medium reservoir configured to receive a portion of the fluid medium, and a flow diverter assembly disposed in a fluid medium flow path between the syringe and the delivery catheter. The syringe includes a chamber for receiving the fluid medium therein. The flow diverter assembly is configured to divert the portion of the fluid medium from the chamber of the syringe away from the delivery of the medium through the delivery catheter conduit during injecting with the syringe, and simultaneously increase medium fluid flow resistance with increasing pressure level of the fluid medium within the flow diverter assembly.

A system for treatment of tissue includes a fixation apparatus and a delivery tool releasably carrying the fixation apparatus. The fixation apparatus includes first and second anchors and an adjustable band connecting the anchors. The band includes a cinch line and a tether connected to one of the anchors. The delivery apparatus includes a body, a tubular shaft, a displacement rod within the tubular shaft, and an actuator.

Apparatus for the treatment of tissue

This disclosure presents methods for treating a defect in soft tissue of a patient. The methods employ fixation delivery apparatuses and fixation apparatuses positioned, at least in part, in or on the soft tissue to be repaired. In some aspects, these techniques include the use of this includes a fixation apparatus that includes at least one bone anchor connected to at least one tissue anchor by a shortenable elongate member.

Method for the treatment of tissue

The present invention provides methods and devices for annulus disc repair with and without the use of a patch or stent. The methods and devices are particularly suited to the repair and/or reconstruction of the spinal disc wall (annulus) after surgical invasion or pathologic rupture, with reduced failure rate as compared to conventional surgical procedures.

Methods and devices for spinal disc annulus reconstruction and repair

The present invention provides methods and devices for treating the annulus of an intervertebral disc. The methods and devices can employ an expandable treatment device which is deployed at least partially in the subannular space. Fixation devices and methods are also disclosed, which help to secure the treatment device in place.

Method and apparatus for the treatment of the intervertebral disc annulus

Devices, systems and methods are described by which the blood pressure, nervous system activity, and neurohormonal activity may be selectively and controllably reduced by activating baroreceptors. A baroreceptor activation device is positioned near a baroreceptor, preferably a baroreceptor located in the carotid sinus. A control system may be used to modulate the baroreceptor activation device. The control system may utilize an algorithm defining a stimulus regimen which promotes long term efficacy and reduces power requirements/consumption. The baroreceptor activation device may utilize electrodes to activate the baroreceptors. The electrodes may be adapted for connection to the carotid arteries at or near the carotid sinus, and may be designed to minimize extraneous tissue stimulation.

Electrode structures and methods for their use in cardiovascular reflex control

A system for providing baroreflex stimulation comprises a sensor to detect a parameter and provide a signal indicative of the parameter and a baroreflex stimulator. The baroreflex stimulator includes a driver to provide a control signal adapted to deliver a baroreflex therapy and a controller to receive the signal indicative of the parameter and modulate the control signal based on the signal indicative of the parameter to change the baroreflex therapy from a first baroreflex therapy to a second baroreflex therapy.

Automatic baroreflex modulation responsive to adverse event

Apparatus and methods for treating or repairing an intervertebral disc are disclosed. The apparatus and methods may be used to treat or repair a tear, rent, incision or delamination of the annulus fibrosus of an intervertebral disc. The apparatus and methods can employ anchor deployment apparatus, fixation apparatus and patches positioned in or on aspects of an intervertebral disc for treatment or repair of the intervertebral disc or its components.

Apparatus and methods for the treatment of the intervertebral disc

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Orono, MN, United States of America

Matthew M Burns