Eli Lilly and Company

Matthew John Valli

James Allen Monn

Steven Marc Massey

David Andrew Coates

Yanping Xu

Darryle D Schoepp

Quanrong Shen

Jeffrey Michael Schkeryantz

Kevin Robert Fales

John Rowley Wetterau, Ii

Carmen Dominguez Fernandez

Dariusz Stanislaw Wodka

Jeffrey Allen Peterson

Quanrong ' Shen

John Rowley Wetterau Ii

Jeffrey Alan Peterson

Yangping Xu

The invention provides compounds of the formula: (A), pharmaceutically acceptable salts, pharmaceutical compositions thereof and methods of using these compounds, salts, or compositions to treat hyperphosphatemia, chronic kidney disease, and/or the cardiovascular disease associated with chronic kidney disease. 

Condensed thiophene derivatives useful as NaPi-IIb inhibitors

Hydantoin derivatives

Compounds of the formula ##STR1## in which R.sup.1 and R.sup.2 are as defined in the specification, and non-toxic metabolically labile ester and amides thereof are useful as modulators of metabotropic glutamate receptor function.

Excitatory amino acid receptor modulators

The present invention relates to compounds of the formula ##STR1## in which R.sup.1 is defined in the specification, and non-toxic metabolically labile esters and amides thereof are useful as modulators of metabotropic glutamate receptor function.

Compounds of the formula ##STR1## in which X represents a bond, S, SO or SO.sub.2 ; and R is as defined in the specification are useful as modulators of metabotropic glutamate receptor function.

Excitatory amino acid receptor antagonists

Compounds for formula I ##STR1## in which X represents O, NR.sup.a, S, SO or SO.sub.2 and R is as defined in the specification; and non-toxic metabolically labile esters or amides thereof; and pharmaceutically acceptable salts thereof are useful as modulators of metabotropic glutamate receptor function.

Excitatory amino acid derivatives

The present invention provides novel compounds that affect certain excitatory amino acid receptors, and are useful in the treatment of neurological disorders and psychiatric disorders.

Pyrrolidinyl di-carboxylic acid derivatives as metabotropic glutamate

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Zionsville, IN, United States of America

Matthew John Valli