University of Texas System

The Texas A&m University System

Matthew J Herpin

Hugh D Smyth

Carolyn L Cannon

Parth N Shah

Justin A Smolen

Ashkan K Yazdi

Robert O Williams, Iii

Hugh D C Smyth

Zachary N Warnken

Miguel Orlando Jara Gonzalez

Hyo-Jong Seo

Ashlee D Brunaugh

The claimed invention is directed to the use of a composition for use as an antimicrobial comprising an antimicrobial agent. In certain embodiments, the composition is used for treating or ameliorating inflammation in a subject and comprises an anti-inflammatory agent. The anti-inflammatory agent may include an NSAID, such as ibuprofen or diclofenac. The composition may further include solvents, anti-bacterial agents, anti-fungal agents, anti-parasitic agents, anti-viral agents, and buffers. The composition may include particles that have been processed via jet milling to reduce a diameter of the particles and to improve a flowability of the particles.

Antimicrobial and anti-inflammatory compositions

The present disclosure provides pharmaceutical compositions of niclosamide that may be administered either orally or by inhalation. These compositions may allow the achievement of a therapeutically effective dose of niclosamide to the lungs or the gastrointestinal tract. These compositions may be used to treat one or more diseases or disorders such as a viral infection or cancer.

Pharmaceutical compositions of niclosamide

There is provided methods for administering a toroidal pharmaceutical composition to a subject. The method includes dispensing a toroidal pharmaceutical composition, and allowing the toroidal pharmaceutical composition to contact a target organ of the subject, thereby administering the toroidal pharmaceutical composition. There are additionally provided toroidal aerosol delivery systems.

Toroidal pharmaceutical formulations

Growing community of inventors

Austin, TX, United States of America

Matthew J Herpin