Nanovis, LLC

Matthew Hedrick

Chang Yao

Daniel Refai

John Williams

Greg Hoffman

John Gorup

Alan McGee

Heidi Rorick

Ganesan Balasundaram

An antimicrobial medical device that includes a substrate having a metal surface that is made from a metal or metal alloy that may include stainless steel, cobalt, and titanium. Disposed on the metal surface is a first antimicrobial oxide layer that includes an antimicrobial metal that may include silver, copper, and zinc, and combinations thereof. The atoms of antimicrobial metal in the first antimicrobial oxide layer are of a first concentration. The first antimicrobial oxide layer is positioned in a direction opposite that of the metal surface. The device further includes a second antimicrobial oxide layer that includes an antimicrobial metal that may be silver, copper, and zinc, and combinations thereof. The atoms of the antimicrobial metal present in the second antimicrobial oxide layer are of a second concentration. The first concentration and the second concentration are not equal. Methods for making the antimicrobial medical device are also disclosed.

Anti-microbial device and method for its manufacture

The present invention relates to a modified polymeric material. The modified polymeric material includes a polymer having a modified surface, where the modified surface includes nano, micron, and/or submicron scale features. The present invention also relates to an implant comprising the modified polymeric material. The present invention further relates to processes for making the modified polymeric material and the implant.

Method for producing nanosurfaces with nano, micron, and/or submicron structures on a polymer

Lumbar interbody spacer implant

Cervical interbody spacer implant

Intervertebral body spacer implant

Lumbar-sacral interbody spacer implant

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Carmel, IN, United States of America

Matthew Hedrick