Wisconsin Alumni Research Foundation

Matthew G Erickson

Thomas M Grist

James Hartman Holmes

Krishna Nagaraj Kurpad

Sean Fain

Robert M Corn

Bernard Weisblum

Andrew T Ulijasz

Emily A Smith

Matthew J Wanat

An RF coil assembly for an MRI system includes a resonator formed by a cylindrical shield and pairs of opposing conductive legs disposed symmetrically around a central axis and extending the axial length of the shield. Drive circuitry for each pair of opposing conductive legs includes a current balun that maintains substantially equal and opposite currents in the two conductive legs. Terminal susceptance elements are used to maintain maximum currents and minimum voltage at the midpoints of the conductive legs. Multinuclear measurements can be made simultaneously at different Larmor frequencies.

RF coil assembly for magnetic resonance imaging and spectroscopy systems

An RF coil assembly for an MRI system includes a resonator formed by a cylindrical shield and pairs of opposing conductive legs disposed symmetrically around a central axis and extending the axial length of the shield. One set of conductive leg pairs is tuned to operate at the Larmor frequency ofC and another set is tuned to operate at the Larmor frequency ofH. Drive circuitry operates the RF coil assembly to produceH spin magnetization which is transferred toC magnetization by the nuclear overhauser effect and to acquire MR data from theC spins. Multinuclear measurements can be made simultaneously at different Larmor frequencies.

RF coil assembly and method for practicing magnetization transfer on magnetic resonance imaging and spectroscopy systems

Disclosed are methods for making surface plasmon resonance-capable arrays wherein molecules, such as proteins or nucleic acids, or cells, are adhered to a metal substrate. The metal substrates are modified by depositing an &#x3c9;-modified alkanethiol monolayer to the substrate and then contacting the &#x3c9;-modified monolayer with a heterobifunctional linking compound. Biomolecules or cells can then be attached to the heterobifunctional linking compound. Also disclosed are arrays wherein glutathione-containing molecules are immobilized on the substrate and GST-containing molecules are then specifically immobilized onto the substrate, taking advantage of the affinity between glutathione and GST.

Fusion protein arrays on metal substrates for surface plasmon resonance imaging

Growing community of inventors

Madison, WI, United States of America

Matthew G Erickson