The Procter Gamble Company

The Proctor 'Gamble Company

Warner Chilcott Company, LLC

Akebia Therapeutics, Inc.

Warner Chilcott, LLC

Matthew Eugene Pokross

Artem G Evdokimov

Richard Masaru Kawamoto

Angelique Sun Boyer

Richard Lee Walter, Jr

Marlene Jan Mekel

The crystal structure of ligand-bound EGLN1 catalytic domain of prolyl hydroxylase is disclosed. These coordinates are useful in computer aided drug design for identifying compounds that regulate EGLN1 prolyl hydroxylase and thereby regulate HIF-regulated disorders.

Crystal of hypoxia inducible factor 1 alpha prolyl hydroxylase

The crystal structures of catalytic domain of HPTPbeta, both ligand-bound and ligand-free are described. These structures are useful in computer aided drug design for identifying compounds that bind or activate HPTPbeta and thereby modulate angiogenesis mediated disorders or diseases.

Three dimensional coordinates of HPTPbeta

The crystal structures of catalytic domain of HPTPbeta, both ligand-bound and ligan-free are described. These structures are useful in computer aided drug design for identifying compounds that bind or activate HPTPbeta and thereby modulate angiogenesis mediated disorders or diseases.

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Hamilton, OH, United States of America

Matthew Eugene Pokross