Sanofi-A Ventis Deutschland Gmbh

Sanofi-Anetis Deutschland Gmbh

Sanofi

Matthew Ekman

Yannick Hourmand

Thomas Mark Kemp

Timothy Donald Barrow-Williams

Simon Francis Brereton

Rosie Burnell

Douglas Ivan Jennings

Gareth Roberts

Chris Ward

Sioned Owen

John Slemmen

Michael James Heald

Alastair Robert Clarke

Bernhard Forys

John Hiles

Kirsten Goode

Chris Smith

Christopher James Smith

Irina Lanin

Graham Peter Wilson

Troy Alan Baker

Andrew Martin

Peter Scudamore

Andrew Peter Scudamore

Rosemary Louise Burnell

Carl Escort Tucker

Lilly Hains-Gadd

Ursula Lanin

Yannick Hourman

Douglas A Jennings

Troy Baker

Michael Heald

Carl Tucker

An auto-injector for administering a dose of a liquid medicament includes an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice intended to be applied against an injection site. The syringe is slidably arranged with respect to the housing. A spring capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end (P), operating the syringe to supply the dose of medicament (M), and retracting the syringe with the needle into the covered position. After delivering the medicament, an activator arranged to lock the spring in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring for injection.

Auto-injector

An auto-injector comprising an elongate housing containing a syringe. The housing having an orifice intended to be applied against an injection site. The syringe is slidably arranged with respect to the housing. A spring pushing the needle from a covered position into an advanced position, operating the syringe and covering the needle. An activator arranged to lock the spring prior to manual operation and capable of, upon manual operation, releasing the spring means for injection. A first gear arrangement and a second gear arrangement arranged fro converting torque from a first end and a second end of the torsion spring into a translative force. The first end groundable in the housing while the second end acts on a plunger through the second gear arrangement for advancing the needle and supplying the dose.

According to the invention, an auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe filled with the medicament (M), a needle shroud arranged with respect to the housing and adapted to rest on the skin of a patient receiving an injection, a releasable drive means arranged within the housing that is capable of, upon release, translating the needle shroud in a proximal direction (P) towards a safe position (PS) and a rotating collar rotatably arranged within the housing. The needle shroud in the safe position (PS) surrounds the injection needle after the injection has been carried out. The rotating collar engages the needle shroud in a manner that forces the rotating collar to rotate within the housing when the needle shroud is translated in the proximal direction (P).

An auto-injector includes a housing, a sleeve, a plunger rod, and a drive spring. The sleeve is sized to receive at least a distal portion of a syringe. The syringe is substantially symmetric about at least two planes that are perpendicular to one another. The plunger rod has an axially-extending portion that is substantially symmetric about the at least two planes, and a flange. The auto-injector has (i) a first state in which at least two axially-extending resilient arms hold the plunger rod in a first position relative to the sleeve to prevent a medicament from being dispensed from the syringe and (ii) a second state in which the at least two axially-extending resilient arms are allowed to deflect radially inward to release the plunger rod from the sleeve to allow the medicament to be dispensed from the syringe.

According to the invention, an auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe filled with the medicament (M), a needle shroud slidably arranged with respect to the housing and adapted to rest on the skin of a patient receiving an injection, a releasable drive means arranged within the housing that is capable of, upon release, translating the needle shroud in a proximal direction (P) towards a safe position (PS) and a rotating collar rotatably arranged within the housing. The needle shroud in the safe position (PS) surrounds the injection needle after the injection has been carried out. The rotating collar engages the needle shroud in a manner that forces the rotating collar to rotate within the housing when the needle shroud is translated in the proximal direction (P).

An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Plunger rod for an auto-injector

Auto-injector methods

Growing community of inventors

Cheshire, United Kingdom

Matthew Ekman