Johnsondiversey, Inc.

Oval Medical Technologies Limited

Meridian Medical Technologies, Inc.

Diversey, Inc.

Quadrant Technologies Limited

Geonomics Global Games Limited

Orion Corporation

Societe De Conseils De Recherches Et D'applications Scientifiques (s.c.r.a.s.)

S. C. Johnson Commercial Markets, Inc.

Aventis Pharma Limited

Ipsen Pharma

Matthew Egerton Young

Curtis Hans Hubmann

Reuben Wu

Elizabeth Anne Slater

Robert C Halstead

Richard I Simpson

Sophie Rebecca Raven

John A Boticki

John Glyndwr Wilmot

Ralph Lamble

Neil Richard Harrison

Michael H Bertucci

Mark T MacLean-Blevins

Stuart Brian William Kay

Colin James Mathews

Robert L Hill

Michael W Ligotke

Christopher John Hurlstone

Grant Smetham

Craig Malcolm Rochford

Jose Alberto De Los Rios

Joseph William Daintrey

Congyi Huang

Stephen Philip Kirkwood

Dominic Charles Reber

Martin Joseph Murphy

James Allan Oakes

Jonathan Lawson

Valerio Lelio Cereda

Benjamin Guy Arbib

Henry Edward Oakes

Martyn James Young

Susanna Elizabeth McRobert White

Michael Charles Savill

Mark D Gerhart

Cormac O'Prey

Roland Cherif-Cheikh

Paul Greenhalgh

Thierry Rimlinger

Dalita R Tomellini

Melinda F Penney

Christophe Aubert

Martin J Murphy

C Michael Mesa

Kevin Joseph Markey

Fabrice Bonacci

Esa Muttonen

Simon R Gainey

Jussi Haikarainen

Gerald L Wannarka

Kari Sepp&auml;l&auml;

Serge Barneaud

Christopher Ferris

Mark Bumb Bremley

Julian Dixon

Richard L Simpson

Marcus Agunloye

Elizabeth Stares

Jarkko Munukka

James Welsh

Stuart Kay

Stephen Pilip Kirkwood

Julian Richard Dixon

Grant Timothy Lewis Smetham

Sarah Jane Cors

Jonathan Oakley

Wayne O'Hara

Dean Ray Maune

Helen Margaret Crosby

Lain R Simpson

Melinda Fischer Penney

Rebecca Sophie Raven

Lian R Simpson

Curtis H Hubmann

Iain R Simpson

Mark T Maclean-Blevins

Kari Seppala

Dalita Rosemarie Tomellini

The invention provides in one aspect a drug delivery device comprising a drug container assembly containing a drug, and a plunger positioned within the container assembly, the drug container assembly having an outlet for dispensing the drug, wherein, in an initial position, the outlet is sealed; a drive mechanism comprising a first stored energy source operable to apply pressure on the plunger or the drug container to pressurise the drug, and a first release mechanism operable to unseal the outlet after the drug has been pressurised. In another aspect, there is provided a drug delivery device comprising a housing, including an external housing portion configured to be held in use and a drug containing portion containing a drug, a needle assembly comprising a needle fixed to a needle hub, the needle hub configured to move relative to the drug containing portion from an initial position within the housing to an insertion position in which the needle extends beyond the housing, a first stored energy source configured to move the needle hub from the initial position to the insertion position, and a plunger within the housing and configured to move relative to the drug containing portion to eject the drug through the needle when the needle is in the insertion position.

Automatic drug delivery devices

Injector

An automatic drug delivery device is described, comprising: a housing (); a skin sensor element () coupled to the housing and movable relative to the housing, wherein the skin sensor element is biased into a front position relative to the housing and is movable to a rear position relative to the housing when the skin sensor element is pressed against an injection site; a needle assembly comprising a hypodermic needle (), the hypodermic needle extending outside of the housing when the device is in a needle insertion configuration; a drug delivery mechanism comprising a stored energy source (), within the housing; wherein the drug delivery mechanism is released when the skin sensor element is moved from the front position towards the rear position and wherein the stored energy source is arranged to expand along an axis that is offset from an axis of travel of the needle assembly in use; a needle retraction mechanism configured to withdraw the hypodermic needle into the housing when the needle retraction mechanism is released; wherein the needle retraction mechanism is coupled to the skin sensor element such that when the skin sensor element is moved from the rear position towards the front position, and the needle is in the needle insertion position, the needle retraction mechanism is released.

Autoinjector with retracting needle

There is provided drug delivery devices comprising a drug container assembly with a needle and automatic needle insertion and drug delivery mechanisms. Aspects of the devices described include a noise-generation mechanism to indicate the completion of drug delivery, a mechanism for triggering drug delivery following needle insertion, front-end activation of the device and a safety mechanism for covering the needle after use and methods of assembly of the devices.

Drug delivery device

A dispenser for mixing and dispensing a liquid chemical concentrate with a diluent from a container. The dispenser includes two slidable eductors one of which is also rotatable. Both a high and low flow rate can be obtained with simultaneous adjustment of concentration of the chemical concentrate. The dispenser has a high degree of accuracy of the amount of dilution of the chemical concentrate as well as positive positioning of the high and low flow rate.

Multiple function dispenser

The invention provides a syringe for dispensing a drug (), comprising: a rigid syringe body, &#x2014;a first container (), in contact with and enclosing the drug; and a second container (), enclosing the first container, the second container being less gas permeable than the first container, wherein the second container partially or fully forms the rigid syringe body or is held within the rigid syringe body. The invention preserves the drug but allows the drug to be easily accessed without the need for a user to remove a gas barrier structure as a separate action in addition to the other actions needed to deliver the drug.

Pre-filled syringe or autoinjector

The invention provides a delivery mechanism for an autoinjector comprising: a first drive member configured to drive a first component in an axial direction; a second drive member configured to drive a second component in an axial direction; and a release mechanism configured to control a sequence of release of the first drive member and the second drive member, wherein the release mechanism is positioned at least partially within the first or second drive member.

Delivery mechanism for an autoinjector

A pre-filled drug delivery device, comprising a housing, a drug container within the housing and containing a drug; a plunger held within the drug container, movement of the plunger within the drug container being operative to dispense the drug from the drug container through an outlet; and a drive mechanism within the housing including a stored energy source and a plunger rod held in locked position against the stored energy source prior to activation of the device, wherein on activation of the device the stored energy source moves the plunger rod such that the plunger rod moves the plunger within the housing wherein the plunger rod comprises a longitudinal shaft formed from sheet metal, wherein the sheet metal defines a plane, and wherein the sheet metal is deformed so that the longitudinal shaft comprises an out-of-plane engagement surface, the out-of-plane engagement surface configured to engage a retaining surface on the housing or on a component of the drive mechanism, to hold the plunger rod in the locked position.

Drug delivery device with pressed metal plunger rod

A dispenser for mixing and dispensing a liquid chemical concentrate with a dilutent from a container. The dispenser includes two slideable eductors one of which is also rotatable. Both a high and low flow rate can be obtained with simultaneous adjustment of concentration of the chemical concentrate. The dispenser has a high degree of accuracy of the amount of dilution of the chemical concentrate as well as positive positioning of the high and low flow rate.

The invention provides in one aspect a drug delivery device comprising a drug container (), and a plunger () positioned within the container assembly, the drug container assembly having an outlet for dispensing the drug, wherein, in an initial position, the outlet is sealed; a drive mechanism comprising a first stored energy source () operable to apply pressure on the plunger or the drug container to pressurize the drug, and a first release mechanism operable to unseal the outlet after the drug has been pressurized. In another aspect, there is provided a drug delivery device comprising a housing, including an external housing portion configured to be held in use and a drug containing portion containing a drug, a needle assembly comprising a needle fixed to a needle hub, the needle hub configured to move relative to the drug containing portion from an initial position within the housing to an insertion position in which the needle extends beyond the housing, a first stored energy source configured to move the needle hub from the initial position to the insertion position, and a plunger within the housing and configured to move relative to the drug containing portion to eject the drug through the needle when the needle is in the insertion position.

There is provided drug delivery devices including a drug container assembly with a needle and automatic needle insertion and drug delivery mechanisms. Aspects of the devices described include a noise-generation mechanism to indicate the completion of drug delivery, a mechanism for triggering drug delivery following needle insertion, front-end activation of the device and a safety mechanism for covering the needle after use and methods of assembly of the devices.

Growing community of inventors

Cambs, United Kingdom

Matthew Egerton Young