Kite Pharma, Inc.

Arsenal Biosciences, Inc.

Matthew Drever

Jonathan Belk

Anzhi Yao

Amy E Gilbert

Samuel T Haile

Samuel A Williams

Duy Nguyen

Catherine A Hartzell

Angela Boroughs

Levi Gray-Rupp

Thomas Gardner

Zhen Jian Zhou

Raghavender Chivukula

Amy-Jo Casbon

Edward Hai Dhow Liao

Eugene Bolotin

Provided are antibodies, fragments thereof, chimeric antigen receptors (CARs) and T cell receptors (TCRs) comprising one or more of the dual TACI-BCMA binding domains disclosed herein. Provided are compositions, cells and cell therapies comprising the same. Further provided are methods of treatment.

TACI binding molecules

Provided herein are antibodies and chimeric priming receptors that bind PSMA and antibodies and chimeric antigen receptors that bind CA9. Also provided are systems of chimeric priming receptors that bind PSMA and chimeric antigen receptors that bind CA9, cells expressing such systems, and methods of use thereof.

Systems targeting PSMA and CA9

Provided are antibodies, fragments thereof, chimeric antigen receptors (CARs) and T cell receptors (TCRs) comprising one or more of the anti-PMCA antigen binding domains disclosed herein. SynNotch receptors that comprise an anti-PSCA binding domain Provided are polynucleotides encoding antibodies, fragments thereof, CARs, T cell receptors (TCR) and SynNotch receptors. Provided are compositions, cells and cell therapies comprising the same. Further provided are methods of treatment.

Prostate cancer chimeric antigen receptors

Growing community of inventors

Concord, CA, United States of America

Matthew Drever