Siemens Medical Solutions Usa, Inc.

General Electric Company

Siemens Aktiengesellschaft

The Boots Company Plc

Perspectum Limited

Matthew David Kelly

Timor Kadir

Jerome Declerck

Jens Kaftan

Thomas George Wright

Kinda Anna Saddi

Guenther Platsch

Brion Daryl Sarachan

Christopher Reynolds Hammond

Bernard Bendriem

Ludovic Sibille

Kevin Scott Hakl

Michael J Brady

John Michael Brady

David Kerr

David Schottlander

Christian Mathers

Antonios Makropoulos

Azadeh Firouzian

Marija Haramija

Julien Michel Yvon Willaime

Rachel Susannah Midgley

Mark Robert Austin

Helen Sisson

Julian Cocking

Julian Richard Cocking

According to the present invention there is provided a multi-phase, fluid skincare composition comprising (a) at least one cream phase; and (b) at least one gel phase; wherein the cream phase and the gel phase are visually distinct phases that are packaged in physical contact; wherein the viscosity ratio of the cream phase to the gel phase is 1.25 or greater:1 or 1:1.25 or greater, preferably 1.25 or greater:1; wherein the viscosity of the cream phase is at least 15 Pa-s; wherein the viscosity of the gel phase is at least 10 Pa-s; wherein the cream phase and the gel phase are present in the composition at a level such that the weight ratio of cream phase to the gel phase is within the range of from 65:35 to 35:65; and wherein the viscosity is measured at 23° C. The present invention also provides a collapsible tube having an outlet bore and containing the composition as defined above, wherein the tube is filled such that, when the composition is extended from the outlet bore, the extruded composition comprises the cream phase and the gel phase that are visually distinct from one another and within a weight ratio of the cream phase to the gel phase of between 65:35 and 35:65 across the cross-section of the extrusion. The present invention also provides a use of the composition defined above for the purpose of one or more of moisturising the skin, including hydrating the skin, improving the radiance of the skin, improving skin suppleness, reducing skin tightness, nourishing skin and/or reducing dryness. The present invention also provides a use of the composition defined above for the purpose of topical application to any one or more of the face, the neck skin and/or the decollete, preferably the face.

Skincare compositions

A method of providing a quantitative volumetric assessment of organ health or a quantitative map of an organ. The method comprises obtaining a volumetric map of organ health comprising information defining a state of tissue health across at least part of an organ, receiving an input defining at least one organ section, determining an assessment organ volume based at least partly on the at least one defined organ section, calculating an organ-viability measure for the assessment organ volume based at least partly on information within the volumetric map defining the state of tissue health across the organ volume, and outputting an indication of the organ-viability measure.

Method and apparatus for providing a quantitative volumetric map of an organ or an assessment of organ health

In a method for retrieval of similar findings from a hybrid image dataset, a database of hotspots is prepared, wherein the hotspots are identified by binary strings encoding descriptors, and identify binary strings stored in the database are identified that resemble a new binary string.

System and method for retrieval of similar findings from a hybrid image dataset

In a method and apparatus for reducing variability of representations of regions of interest in reconstructions of original imaging data, a processor performs a reconstruction on the original imaging data to provide original image data, applies a filter to the original image data to provide filtered image data, displays the original image data to a user as an original image, at said display monitor, receives input parameters from the user to define a volume of interest, applies the input parameters to the filtered image data to generate a contour defining the volume of interest in the filtered image data, and displays the contour defining the volume of interest in the filtered image data to the user on the original image at said display monitor.

Method and apparatus for reducing variability of representations of regions of interest on reconstructions of medical imaging data

A voice controlled system uses context-sensitive interpretation of voice comments received by a voice recognition system to identify a region of patient image data identified by a verbal comment.

Context-sensitive identification of regions of interest in a medical image

In a method and apparatus for providing a visualization image and a reference image for a patient, with only one reconstruction being implemented, raw scan data from the patient are reconstructed into a visualization image, and the reference image is generated, without another reconstruction, by applying a filter to the visualization image to obtain a simulated reference image, using a value of a filter parameter that is specific for the patient. The patient-specific filter parameter is determined by comparing image-derived properties of an accessed, previously-reconstructed reference image and the reference image, and the filter parameter is adapted to reduce differences in the image-derived properties of the respective images.

Method and apparatus for calibration of medical image data

In a method and apparatus for automatic background region selection for lesion segmentation in medical images, a patient medical image dataset is loaded into a computer and an image region is delineated to obtain a segmentation containing a lesion. A background region is created from the segmentation representing the patient organ.

Automatic background region selection for lesion delineation in medical images

In a method and apparatus for generating an enhanced image for display from medical imaging data of a subject, a feature of interest in the imaging data elongated in at least one dimension is determined. A location of a line through the imaging data along the feature of interest is obtained, and a projection image along the line is generated from the imaging data.

Method and apparatus for generating an enhanced image from medical imaging data

In a method and apparatus for correcting image data from a medical imaging scan of a subject, into which subject a specified amount of an imaging substance has been introduced, a region of the image data, containing an anomalous proportion of the imaging substance introduced, is identified. For the identified region a regional value of a variable in the image data associated with the imaging substance is determined. The regional value is used to determine the proportion of the substance in the region, and the proportion is subtracted from the specified amount of the imaging substance.

Method and apparatus for correcting medical imaging data

A method for facilitating comparison of image data from a given medical imaging protocol with archive image data, includes obtaining subject image data from a scan of a subject using the medical imaging protocol, obtaining archive image data differing from the subject image data in a given variable, determining a modifier usable to reduce the difference between the archive and subject image data, using the modifier to modify one of the subject image data and the archive image data to reduce the difference, and comparing the modified archive or subject image data with the subject or archive image data.

Equalizing smoothing for a scan comparison to database

In a method and an apparatus to visualize nuclear medicine data from different modalities in a single image, image data sets acquired with different modalities are aligned with a data set representing corresponding anatomical data. The image data in each data set are segmented into separate regions, representing respective structures of interest, with reference to a segmentation derived from anatomical data. For each region, a corresponding segment of image data is selected from a selected image data set. The selected segments of the image data set are combined to generate a multi-fused image of the regions, by applying spatially dependent look-up tables to the multiple image data sets, thereby to determine whether each data set is hidden or displayed in each region.

Method for combining multiple image data sets into one multi-fused image

In a method to generate a nuclear medicine image reconstructed from an average of multiple subsets of acquired counts of a dataset, having an image quality characteristic aligned with that of a corresponding image obtained from a reconstruction of all counts of the dataset, a phantom data acquisition is used to determine an appropriate post-processing step necessary to align each image quality characteristic which provides a desired alignment of a given image quality characteristic. The determined post-processing step is applied to the combination of the multiple reconstructions.

Method for frame averaging post-filter optimization

In a method and apparatus for identifying a region of interest in medical imaging data of a subject is described, an intensity projection image is generated from the medical imaging data. The medical imaging data is then processed to find one or more maxima in the medical imaging data. The found maxima are compared with the intensity projection image, and one of the maxima which is not represented in the intensity projection image is identified.

Method and apparatus for identifying regions of interest in medical imaging data

In a method or apparatus for generating, from medical image data of a subject from a functional imaging modality, a modified intensity projection image for display. An intensity projection image data set is obtained from the image data. A segmentation for the image data is obtained. Based on information from the segmentation, a modified display property is calculated for at least one voxel of the intensity projection image data set.

Methods and apparatus for generating a modified intensity projection image

In a method or apparatus for identifying a region of interest in a medical image of a subject, at least one local maximum region of the image is determined for which a value of a given variable is a local maximum value. A user-selection of an initial voxel in the image is registered. As the region of interest, a connected set of voxels for which values of the given variable are greater than a threshold is selected, the selected set of voxels comprising a first local maximum region at a distance from the user-selected voxel, and the threshold being a given fraction of the local maximum value of the first local maximum region in the set.

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Botley, United Kingdom

Matthew David Kelly