Dexcom, Inc.

Matthew D Wightlin

Peter C Simpson

Jack Pryor

Mark C Brister

Robert James Boock

Apurv Ullas Kamath

James R Petisce

Sean T Saint

John Nolting

Steve Masterson

Vance Swanson

Sebastian Bohm

Aarthi Mahalingam

Paul V Neale

Daiting Rong

James H Brauker

Paul V Goode, Jr

Michael J Estes

Mark C Shults

Jacob S Leach

Thomas Arnold Peyser

Shawn Larvenz

Mark Dervaes

Dubravka Markovic

Antonio C Llevares

Jennifer Blackwell

Stephen J Vanslyke

Andrew Attila Pal

Sebastian Böhm

Hari Hampapuram

Naresh Chandra Bhavaraju

Jason M Halac

Aditya Sagar Mandapaka

Eli Reihman

Katherine Yerre Koehler

Eric Cohen

Leif N Bowman

Brian Christopher Smith

Arturo Garcia

Douglas William Burnette

Anna Leigh Davis

Richard Chien Yang

Ying Li

Laura J Dunn

John Michael Dobbles

Nicholas Polytaridis

Kaushik Aroonkumar Patel

Thomas Hall

Scott M Belliveau

Lauren Hruby Jepson

Disha B Sheth

Benjamin Elrod West

J Michael Dobbles

Jeff Jackson

Kum Ming Woo

Melissa A Nicholas

Jason Mitchell

Tom Miller

Kenneth San Vicente

Eric Johnson

Mohammad Ali Shariati

Lisa Nguyen

Seth R Brunner

Arthur Chee

Ted Tang Lee

Zebediah L McDaniel

Victor Ha

Rui Ma

Huashi Zhang

Alexandra Elena Constantin

Phong Lieu

Monica A Rixman

Jonathan Hughes

Becky L Clark

Subrai Girish Pai

Chris W Dring

David DeRenzy

Matthew Lawrence Johnson

Vincent Peter Crabtree

Patrick Wile McBride

Michael Levozier Moore

Stephen Alan Reichert

Sumitaka Mikami

James Stephen Amidei

Philip Mansiel Pellouchoud

Curtis Hanson

David I-Chun Lee

Liang Wang

Alexander Leroy Teeter

Katherine Yerre Grubstein

Minda McDorman Grucela

Vance E Swanson

Darin Edward Chum Dew

Steven David King

Robert Patrick Van Tassel

James Jinwoo Lee

Monica A Rixman Swinney

Tim Ray Gackstetter

Roger Schneider

George Vigil

Systems and methods of use involving sensors having a signal-to-noise ratio that is substantially unaffected by non-constant noise are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.

Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise

Adhesive pad systems that provide longer lasting adherence of the mounting unit to the host's skin are provided. Some systems include a reinforcing overlay that at least partially covers the adhesive pad. The reinforcing overlay may be removable without disturbing the sensor so that the overlay may be replaceable.

Systems and methods for securing a continuous analyte sensor to a host

The present invention relates generally to systems and methods for processing, transmitting, and displaying data received from continuous analyte sensor, such as a glucose sensor. In some embodiments, the continuous analyte sensor system comprises a sensor electronics module that includes power saving features. One feature includes a low power measurement circuit that can be switched between a measurement mode and a low power mode, in which charging circuitry continues to apply power to electrodes of a sensor during the low power mode. In addition, the sensor electronics module can be switched between in a low power storage mode higher power operational mode via a switch. The switch can include a reed switch or optical switch, for example. A validation routine can also be implemented to ensure an interrupt signal sent from the switch is valid. The continuous analyte sensor can be physically connected to a sensor electronics module, which is in direct wireless communication with a plurality of different display devices.

Advanced continuous analyte monitoring system

Systems and methods are provided that address the need to frequently calibrate analyte sensors, according to implementation. In more detail, systems and methods provide a preconnected analyte sensor system that physically combines an analyte sensor to measurement electronics during the manufacturing phase of the sensor and in some cases in subsequent life phases of the sensor, so as to allow an improved recognition of sensor environment over time to improve subsequent calibration of the sensor.

Automatic analyte sensor calibration and error detection

Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor systemcomprising two working electrodes and at least one reference/counter electrode is provided. The sensor systemcomprises first and second elongated bodies E, E, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layerthat separates the conductive layerfrom the elongated body, a membrane layer deposited on top of the elongated bodies E, E, and working electrodes″ formed by removing portions of the conductive layerand the insulating layer, thereby exposing electroactive surface of the elongated bodies E, E

Analyte sensors and methods of manufacturing same

Devices and methods are provided for continuous measurement of an analyte concentration. The device can include a sensor having a plurality of sensor elements, each having at least one characteristic that is different from other sensor(s) of the device. In some embodiments, the plurality of sensor elements are each tuned to measure a different range of analyte concentration, thereby providing the device with the capability of achieving a substantially consistent level of measurement accuracy across a physiologically relevant range. In other embodiments, the device includes a plurality of sensor elements each tuned to measure during different time periods after insertion or implantation, thereby providing the sensor with the capability to continuously and accurately measure analyte concentrations across a wide range of time periods. For example, a sensor systemis provided having a first working electrodecomprising a first sensor elementand a second working electrodecomprising a second sensor elementand a reference electrodefor providing a reference value for measuring the working electrode potential of the sensor elements

Analyte sensor

Systems and methods of use involving sensors having a particle-containing domain are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.

Particle-containing membrane and particulate electrode for analyte sensors

Systems and methods for compensating for effects of temperature on implantable sensors are provided. In some embodiments, systems and methods are provided for measuring a temperature to determine a change in temperature in a sensor environment. In certain embodiments, a temperature compensation factor is determined based on a change in temperature of the sensor environment. The temperature compensation factor can be used in processing raw data of an analyte signal to report a more accurate analyte concentration.

Devices, systems, and methods to compensate for effects of temperature on implantable sensors

Devices and methods are provided for continuous measurement of an analyte concentration. The device can include a sensor having a plurality of sensor elements, each having at least one characteristic that is different from other sensor(s) of the device. In some embodiments, the plurality of sensor elements are each tuned to measure a different range of analyte concentration, thereby providing the device with the capability of achieving a substantially consistent level of measurement accuracy across a physiologically relevant range. In other embodiments, the device includes a plurality of sensor elements each tuned to measure during different time periods after insertion or implantation, thereby providing the sensor with the capability to continuously and accurately measure analyte concentrations across a wide range of time periods. For example, a sensor systemis provided having a first working electrodecomprising a first sensor elementand a second working electrodecomprising a second sensor element, and a reference electrodefor providing a reference value for measuring the working electrode potential of the sensor elements

Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure additional analyte or non-analyte related signal. Such measurements may provide a background and/or sensitivity measurement(s) for use in processing sensor data and may be used to trigger events such as digital filtering of data or suspending display of data.

Dual electrode system for a continuous analyte sensor

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Ladera Ranch, CA, United States of America

Matthew D Wightlin