North Carolina State University

Breen, Matthew

Matthew Breen

This invention relates generally to the discovery of an improved method to differentiate histiocytic malignancy from lymphoma or hemangiosarcoma in dogs.

Chromosomal assessment to differentiate histiocytic malignancy from lymphoma and hemangiosarcoma in dogs

This invention is directed to a method of diagnosing bladder cancer in dogs.

Chromosomal assessment to diagnose urogenital malignancy in dogs

The present disclosure provides methods for detecting a high-risk phenotype of a mast cell tumor (MCT) in a biological sample from a mammal, preferably a dog. Kits, PCR probes and primers to detect high-risk MCT are also provided.

Methods of mast cell tumor prognosis and uses thereof

This disclosure is directed to the discovery of an improved method to diagnose malignant melanoma of the oral cavity in the dog.

Method to diagnose malignant melanoma in the domestic dog

Chromosomal assessment to differentiate histiocytic malignancy from lymphoma in dogs

Methods for predicting a disease free time interval (DFI) for a cancer patient under consideration for initial or further chemotherapy treatment are disclosed. The methods include obtaining a biological sample from a patient and detecting a copy number of chromosome region A1 and/or C2. The mean copy number per cell is correlated with a DFI for the subject. The chemotherapy can include doxorubicin and/or L-asparaginase treatment. Also provided are kits for predicting DFI in a subject with cancer and computer readable storage media for performing the presently disclosed methods.

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Raleigh, NC, United States of America

Matthew Breen