University System of Maryland

The University of New Mexico

University of Notre Dame Du Lac

Matthew A Earl

Shuang Luan

Danny Ziyi Chen

Chao Wang

Cedric Xinsheng Yu

David M Shepard

Daliang Cao

Provided herein are methods and systems for designing a radiation treatment for a subject using single arc dose painting. The methods and systems comprise an algorithm or a computer-readable product having the same, to plan the radiation treatment. The algorithm converts pairs of multiple leaf collimation (MLC) leaves to sets of leaf aperture sequences that form a shortest path single arc thereof where the pairs of MLC leaves each aligned to an intensity profile of densely-spaced radiation beams, and connects each single arc of leaf apertures to form a final treatment single arc. Also provided is a method for irradiating a tumor in a subject using single arc dose painting.

Single-arc dose painting for precision radiation therapy

The invention is directed to a radiation therapy method, and in particular, to a method of conducting an intensity modulated arc therapy (IMAT). The invention provides a planning technique that translates traditional static fixed-field IMRT plans into deliverable IMAT plans and allows IMAT to be realized as a routine clinical delivery technique.

ARC-sequencing technique for intensity modulated ARC therapy

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Crownsville, MD, United States of America

Matthew A Earl