Astrazeneca Ab

Mats O Johansson

Staffan Folestad

Ingela Niklasson Björn

Lennart Björk

Anders Klevensparr

An apparatus for use in sampling material on-line in a process system, comprising a sample collector () for receiving a sample of material, an elongate shaft () defining a passageway () carrying a measurement probe () for taking measurements from a colelcted sample, a pressurised fluid supply () connected to the passageway for delivering a pressurised fluid through the passageway to the sample collector for displacing the collected sample and a nozzle () provided at the distal end of the measurement probe () for distributing the pressurised fluid to the sample collector for displacing the collected sample from the sample collector ().

Sampling apparatus

A mixing apparatus for preparing from a plurality of materials, preferably powders, in particular components of a pharmaceutical composition, a mixture having a required homogeneity, comprising a non-rotating mixing vessel (); at least one feeding mechanism for feeding said materials into said vessel (); a stirring means () inside said vessel () for preparing said mixture; and at least one measuring device () for monitoring in-line at one or more locations in said vessel () the homogeneity of the mixture being prepared therein, wherein said at least one measuring device () comprises a unit for directing input radiation into said vessel (), and at least one detector unit () for detecting output radiation formed by interaction of said input radiation with said materials in said vessel ().

Mixing apparatus

An apparatus for use in sampling material on-line in a process system, comprising a sample collector () for receiving a sample of material, an elongate shaft () defining a passageway () carrying a measurement probe () for taking measurements from a collected sample, a pressurised fluid supply () connected to the passageway for delivering a pressurised fluid through the passageway to the sample collector for displacing the collected sample and a nozzle () provided at the distal end of the measurement probe () for distributing the pressurised fluid to the sample collector for displacing the collected sample from the sample collector ().

A mixing apparatus for preparing from a plurality of materials, preferably powders, in particular components of a pharmaceutical composition, a mixture having a required homogeneity, comprising a non-rotating mixing vessel ( ); at least one feeding mechanism for feeding said materials into said vessel ( ); a stirring means ( ) inside said vessel ( ) for preparing said mixture; and at least one measuring device ( ) for monitoring in-line at one or more locations in said vessel ( ) the homogeneity of the mixture being prepared therein, wherein said at least one measuring device ( ) comprises a unit for directing input radiation into said vessel ( ), and at least one detector unit ( ) for detecting output radiation formed by interaction of said input radiation with said materials in said vessel ( ).

A mixing apparatus for and a method of supplying a mixture having a required homogeneity, the mixing apparatus comprising: a mixing device ( ) for mixing a plurality of materials, the mixing device ( ) including a mixing vessel ( ) and having at least one inlet port ( ) and an outlet port ( ); a supply line ( ) connected to the outlet port ( ) of the mixing device ( ); and at least one measuring device ( ) for measuring on-line at at least one point in the supply line ( ) the composition of the mixed material passing in use through the supply line ( ).

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Jonsered, Sweden

Mats O Johansson