Raysearch Laboratories Ab (publ)

Mats Holmstrom

David Andersson

Albin Fredriksson

Hanna Gruselius

Gabriel Carrizo

Adnan Hossain

A method () for generating a treatment plan specifying an irradiation of a patient, the method comprising: a dose inference stage (), including using a model to infer a spatial dose from patient data; a dose mimicking stage (), including executing a robust optimization process to generate a deliverable treatment plan which is consistent with the inferred spatial dose, wherein the robust optimization considers a plurality of scenarios relating to patient data uncertainty.

Automated treatment planning by dose prediction and robust dose mimicking

An estimated or predicted dose for radiotherapy treatment may be generated based on a partial dose map including dose information only for one or more regions of interest within a treatment site, by use of a properly trained machine learning system such as a U-Net or a V-Net. Said partial dose map typically set to fulfil clinical goals. A method of training such a machine learning system is also disclosed.

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VÄRMDÖ, Sweden

Mats Holmstrom