Richter Gedeon Vegyeszeti Gyar Rt

Mate Kovatsits

Sandor Gorog

Gabor T Szabo

Ferenc Trischler

Jozsef Toth

Sandor Holly

Gabor Havasi

Bela Losonczi

Laszlo Csutoras

Erzsebet Francsics

The invention relates to the novel 2,6-bis(chloromethyloxy-carbonyloxymethyl)pyridine of the formula (I) ##STR1## as well as a process for the preparation of this compound, which is a useful intermediate in the preparation of the anti-atherosclerotic 2,6-bis(hydroxymethyl)pyridine bis(N-methylcarbamate) (pyridinolcarbamate) and other drugs. According to the invention, the compound of the formula (I) is prepared by reacting 2,6-bis(hydroxymethyl)pyridine of the formula (II) ##STR2## with chloromethyl chloroformate of the formula (III) ##STR3## in a polar-aprotic, water-immiscible organic solvent, in the presence of a basic substance between about -30.degree. C. and +10.degree. C.

2,6-bis(chloromethyloxy-carbonyloxymethyl)pyridine and a process for

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Leanyfalu, Hungary

Mate Kovatsits