University of California

Massoud L Khraiche

Yu-Hwa Lo

William Freeman

Gert Cauwenberghs

Gabriel A Silva

Deli Wang

Sohmyung Ha

Yi Jing

E J Chichilnisky

William R Freeman

Somhyung Ha

An integrated nanowire device includes a first array of nanowires having a first set of characteristics and a second array of nanowires having a second set of characteristics. A processor is electrical communication with the first and second arrays of nanowires receives the first plurality of charges and generate a processor signal therefrom. The second array of nanowires may be configured to produce a stimulation current in response to the processor signal. The first or second array may be used to generate power for operation of the device, or the arrays may function as a stimulator, sensor combination to enable the device to self-regulate based on localized responses to stimulation. The device may be implanted for use as a neural stimulator.

Integrated nanowire array devices for detecting and/or applying electrical signals to tissue

A prosthetic retina for implantation in an eye having a defective retina is formed from an array of nanowires having a predetermined spatial distribution, density, size and shape implanted in close proximity to the retina. An electrical conductor is formed at a first end of all nanowires in the array of nanowires and placed in contact with a bias source which biases the array. A plurality of electrodes is located on a second end of each of one nanowire or a bundle of nanowires in the array. Each nanowire produces a photocurrent at a corresponding electrode in response to detection of light impinging on the array of nanowires and the photocurrent stimulates one or more neurons adapted for visual perception. In the preferred embodiment, the predetermined spatial distribution mimics a distribution of rods and cones in a normal eye.

Ultra-high photosensitivity vertical nanowire arrays for retinal prosthesis

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San Diego, CA, United States of America

Massoud L Khraiche