Indena S.p.a.

Massimo Ronchi

Ezio Bombardelli

Paolo Morazzoni

Gabriele Fontana

Antonella Riva

Andrea Giori

Cesare Ponzone

Giacomo Mombelli

Elisabetta Frattini

Daniele Ciceri

Fabrizio Corti

Federico Peterlongo

Sabrina Arpini

Paola Di Nicolo

Paola Di Nicolo'

Disclosed are powder solid compositions including a hydroalcoholic extract of Bergamot fruit (var.) and at least one phospholipid. Also disclosed is a process for the preparation of the compositions. The compositions are useful for the prevention and/or treatment of dysmetabolic syndromes, dyslipidemias and type 2 diabetes.

Powder solid compositions, process for their preparation, formulations and use thereof

Disclosed are compositions including berberine combined with pea proteins and one or more surfactants. Also disclosed are processes for the preparation of the compositions, and the formulations and uses thereof.

Compositions comprising berberine

Disclosed are powder solid dispersions including quercetin, phospholipids and a very to freely water soluble carrier. Also disclosed are a process for the preparation of the powder solid dispersions and pharmaceutical, nutraceutical and cosmetic compositions including the solid dispersions.

Powder solid dispersions comprising quercetin, process for their preparation and formulations thereof

Disclosed is a process for the preparation of powder compositions including a lipophilic extract ofspp., a lipophilic extract ofand phospholipids. Also disclosed are powder compositions obtainable by the process and pharmaceutical, nutraceutical and cosmetic formulations including the compositions. Also described is a use of the powder compositions and formulations thereof in the prevention and/or treatment of inflammatory and painful states.

Process for the preparation of powder compositions

The invention relates to a solid dispersion comprising Coenzyme Qand a phospholipid, in the presence of a cellulosic derivative and/or a polymeric material selected from the group consisting of polyvinylpyrrolidone, polyvinyl acetate, poly (methacrylic acid, methyl methacrylate), poloxamers, chitosan, alginates, hyaluronic acid, pectin, pullulan, cyclodextrins, starch polymers, D-alpha-tocopheryl polyethylene glycol 1000 succinate.

Solid dispersions of Coenzyme Q

The present invention relates to compositions containing a combination of a cell proliferation-stimulating agent with vasokinetic properties and an antimicrobial, antifungal and antiviral agent with an anti-inflammatory/analgesic, which is useful in the treatment of peripheral ulcers of various origins, such as diabetic ulcers, ulcers caused by venous stasis of the limbs, bedsores and the associated skin infections. Said combination could be presented as formulations for topical or systemic use.

Compositions for the treatment of peripheral ulcers of various origins

The invention provides formulations containing sanguinarine, chelerythrine or chelidonine or their salts or extracts containing them, mixed with suitable vehicles and/or excipients, for the treatment of common skin warts and verrucas, anal and vulvar warts and psoriatic plaques.

Formulations with sanguinarine, chelerythrine or chelidonine for the treatment of warts, verrucas and psoriatic plaques

The present invention relates to formulations containing extracts ofor other species rich in anthocyanosides,, and optionally. Said formulations are useful in the treatment of disorders of the mouth and its adnexa, the throat and respiratory tract, and in the treatment of influenza.

Formulations for the treatment of disorders of the upper respiratory tract

The present invention relates to compositions comprising benzophenanthridine alkaloids, benzofuran compounds and catechin polyphenols, which are useful in the treatment and prevention of infections of the oral cavity.

Compositions for the treatment and prevention of infections of the oral cavity

The present invention relates to aextract with a high content of caffeoylquinic acids, and a composition containing saidextract with aextract. Said composition is useful in reducing obesity as it reduces cholesterol, triglycerides and blood glucose by sensitising the cells to insulin. This combination, when taken before meals, reduces the appetite, leading to a reduction in body weight. The extracts are preferably formulated inoil, fish oil, or oils rich in unsaturated &#x3c9;-3 fatty acids.

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The present invention relates to aextract with a high content of caffeoylquinic acids, and a composition containing saidextract with aextract. Said composition is useful in reducing obesity as it reduces cholesterol, triglycerides and blood glucose by sensitizing the cells to insulin. This combination, when taken before meals, reduces the appetite, leading to a reduction in body weight. The extracts are preferably formulated inoil, fish oil, or oils rich in unsaturated &#x3c9;-3 fatty acids.

This invention relates to the combination of &#x3b1;-amylase inhibitors prepared fromwith &#x3b1;-glucosidase inhibitors obtained fromand other species. The &#x3b1;-amylase inhibitor is accompanied by a quantity of lectins that reduces the amount of glucose originating from the starches present in the diet, and considerably reduces the appetite after repeated administration. The combination with &#x3b1;-glucosidase inhibitors, such as extracts ofor the thiosugars present in it, further reduce the blood glucose, acting synergically, and consequently reduce the synthesis of fats from carbohydrates.

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Milan, Italy

Massimo Ronchi