Technische Universiteit Eindhoven

Koninklijke Philips Corporation N.v.

Hipermotion B.v.

Gynaecologiepraktijk B.c. Schoot B.v.

Massimo Mischi

Ruud Johannes Gerardus Van Sloun

Marcel Breeuwer

Benedictus Schoot

Hessel Wijkstra

A self-powered vibration mechanism is provided that can be mounted on an existing pedal shaft yet operates independent from the existing pedal. Mechanical isolation or mechanical decoupling permits transferring the vibrating energy to the foot rather than to the pedal shaft and the bicycle. In another embodiment, a full removable pedal with self-powered vibration mechanism can replace an existing pedal.

Self-powered, mechanically-isolated/decoupled vibration mechanism for bicycle pedals

Some embodiments relate to a system and method of estimating the viscoelasticity of a material. The system and method includes

Shear wave viscoelasticity imaging using local system identification

Some embodiments are directed to a method for quantitative visualization of uterine strain. The method includes receiving a number of 2D or 3D image frames acquired via an imaging technique and selecting a number of confidential points, determining the orientation of the uterus using the confidential points, selecting a region of interest, generating a grid of tracking points inside the region of interest and tracking and estimating the displacement of tracking points between frames. From a varying distance between each couple or set of tracking points, a strain is calculated. The orientation of the grid of tracking points and of the calculated strain is dependent on the determined orientation of the uterus.

Two-dimensional and three-dimensional strain mapping for uterine contractions

Some embodiments are directed to a method of estimating a velocity of a contrast agent. The method includes receiving a plurality of video frames that were produced using a dynamic contrast enhanced imaging process, each video frame including a plurality of pixels/voxels. Information from the video frames is used to estimate velocity vectors indicating the velocity and direction of the agent with the vascular networks. The estimated velocity can be used to diagnose cancer, such as prostate cancer. Instead of velocity vectors, agent trajectories can be determined also used for the same purpose.

Imaging of dispersion and velocity of contrast agents

A method of determining microvascular architecture is disclosed. Dynamic contrast-enhanced magnetic resonance data acquired from a contrast agent administered to at least a part of a subject to be examined. From the dynamic contrast-enhanced magnetic resonance data a leakage parameter (k) and a dispersion parameter (k) are computed. Effects of both convective dispersion and extravasation kinetics of contrast agent are taken into account.

Determination of physiological parameters of tissue from dynamic contrast-enhanced MR data

The invention relates to using a perfusion scanning medical imaging technique to generate an image of a perfusable structure of an organism. A fluid is flowing through the structure, and a dose of a traceable agent is present in the fluid. The evolution of the spatial concentration of the agent, e.g., a set of values of the magnitude of the concentration assumed at various moments over a period of time, is determined for a plurality of locations within the structure. The spatial pattern of the evolutions is analyzed and an image is generated on the basis of this analysis in order to enable the medical practitioner to draw conclusions about the dispersion characteristics of the perfusable structure.

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Eindhoven, Netherlands

Massimo Mischi