Zach System S.p.a.

Zach System

Massimiliano Forcato

Livius Cotarca

Massimo Verzini

Giorgio Soriato

Johnny Foletto

Roberto Giovanetti

Nicola Catozzi

Yvon Derrien

Patricia Poirier

Tony Pintus

Corrado Colli

Pierrick Morice

Sebastien Meunier

Laurence Graindorge

Sébastien Meunier

The present invention relates to a process for the preparation of 17-substituted steroids and, more particularly, to an improved method of preparing micro size abiraterone or derivatives thereof in high yield and purity by means of a spherical agglomeration process.

Process for producing a solid form of abiraterone acetate

A process for preparing N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)-phenyl]propan-1-amine hydrochloride salt of formula (I) i.e. Cinacalcet hydrochloride and its intermediates of formulae (VII) and (VIII) wherein Z is chloride or another pharmaceutically acceptable anionic counterion.

Process for preparing Cinacalcet hydrochloride

The present invention relates to a process for the preparation of 17-substituted steroids and, more particularly, to an improved method of synthesizing abiraterone or derivatives thereof in high yield and purity by means of a key 3-formate intermediate.

Process for preparing 17-substituted steroids

A process for preparing N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)-phenyl]propan-1-amine of formula hydrochloride salt of formula (I) i.e. Cinacalcet.HCl and its intermediate of formula (IX) 

Process for preparing cinacalcet

A process for preparing N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)-phenyl]propan-1-amine of formula (I) i.e. Cinacalcet and its intermediates of formulae (V), (Va) and (Vb). 

Process for preparing Cinacalcet

A process for the manufacturing of levetiracetam, wherein said process comprises the steps of: (1) reacting the (&#x2212;)-(S)-alpha-ethyl-2-oxo-1-pyrrolidine acetic acid with a substoichiometric amount of an activating agent in an alcoholic solvent, and (2) subjecting the resulting reaction solution of step (1) to an ammonolysis process with gaseous ammonia.

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Galzignano Terme, Italy

Massimiliano Forcato