Shin-etsu Chemical Co., Ltd.

Masayuki Tonedachi

Fujio Sekigawa

Katsuyoshi Minemura

The invention provides a novel method for providing entric coating on solid dosage forms using an aqueous coating liquid so that the problems inherent to the use of a coating liquid in an organic solvent can completely be eliminated. The inventive method comprises dispersing a finely divided powder of a hydroxypropylmethylcellulose phthalate in an aqueous medium containing triacetin to give an aqueous coating liquid with which the solid dosage forms are coated, for example, by spraying and dried. It is necessary that the preparation of the coating liquid and the coating procedure with the coating liquid are performed throughout while keeping the temperature of the liquid below 25.degree. C. so as that the particles of the hydroxypropylmethylcellulose phthalate are not dissolved in the medium forming a stable dispersion without adhesive coalescence.

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Tokyo, Japan

Masayuki Tonedachi