Chugai Seiyaku Kabushiki Kaisha

Masaya Kakuta

Jun Kikuchi

Yoshimi Imaeda

Hidefumi Mizushima

Tsutomu Arakawa

Tadao Yamazaki

Akira Hayasaka

Yoshiyuki Endo

Yoshiki Hayashi

Masahiko Tanikawa

Naoyoshi Kuroyanagi

Antibody-containing solution formulations including a sugar as a stabilizer. Said solution formulations can further include a surfactant as a stabilizer.

Antibody-containing solution formulations

Antibody-containing solution pharmaceuticals

The present invention provides stabilized preparations containing an antibody in a glycine buffer and/or a histidine buffer and also provides processes for preparing a protein-containing stabilized preparation, comprising adjusting the pH with a basic amino acid or a basic amino acid derivative or a salt thereof.

Stabilized anti-interleukin-6 antibody-containing preparations

A method of quantifying an ethylene oxide based nonionic surfactant in a sample containing a physiologically active protein, characterized in that quantitation is performed by colorimetry, in particular, a method of quantifying an ethylene oxide based nonionic surfactant in a sample containing a physiologically active protein, characterized in that an ammonium thiocyanate/cobalt nitrate reagent (CoSCN reagent) is added to said sample solution and the resulting cobalt thiocyanate complex is quantified by absorbance measurement.

Method of quantifying surfactant

Growing community of inventors

Shizuoka, Japan

Masaya Kakuta