Sawai Pharmaceutical Co., Ltd.

Takara Company, New York, Inc.

Masatoshi Nakatani

Masaru Sugita

Nobuaki Ikeji

Kenji Nozawa

Hiroaki Kikuoka

Provided is an orally disintegrating tablet evaluating method includes: measuring the mass of tablet; placing the tablet on a preparation placement surface of a test solution supply unit; measuring a water absorption time for a test solution to penetrate from one end of the tablet in contact with the surface to the other end of the tablet; measuring the mass of the tablet for which the time for the solution to penetrate has been measured; and calculating the water absorption rate of the tablet by the following formula (1); wherein the tablet is evaluated based on a water absorption rate of the tablet of 0.004 g/sec:water absorption rate of tablet=(mass of tablet after measurement of time for solution to penetrate&#x2212;mass of tablet before measurement of time for solution to penetrate)/(time for solution to penetrate from one end to other end)&#x2003;&#x2003;(1).

Orally disintegrating tablet evaluating method, and orally disintegrating tablet evaluating device

A mouthfeel evaluation method for an orally disintegrating test object is provided, the method including, by a measurement apparatus, giving a predetermined distortion with a predetermine cycle as applying a predetermined pressure to the orally disintegrating test object, adding a predetermined amount of a test liquid to the test object, and measuring a loss tangent of the test object with time.

Mouthfeel evaluation method and mouthfeel evaluation apparatus for orally disintegrating test object

A pair of link plates, each pivotally connected at one end to a seat base and each pivotally connected at their other ends to a seat plate and seat supported thereby, constrain the seat plate and seat to a rearward and upward movement, or a downward and forward movement, with respect to the seat base. The plunger, of a hydraulic cylinder pivotally carried by the seat base, is pivotally connected to the seat plate so that when actuated it induces movement of the seat plate to its rearward and upward position. A seat back is pivotally connected to the seat base and to armrests carried by the seat plate so that movement of the seat in the upward and rearward direction moves the seat back to a downward position aligned with the seat. A footrest linkage is connected between the seat back and a footrest connected to the seat so that movement of the seat back into its downward position moves the footrest into an upward position aligned with the seat and seat back.

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Osaka, Japan

Masatoshi Nakatani