Ishihara Sangyo Kaisha, Ltd.

Masato Omatsu

Hirohiko Kimura

Takahiro Haga

Takanori Suzuki

Toru Koyanagi

Masayuki Morita

Itaru Shigehara

Tadaaki Toki

Kazuhiro Yamamoto

Hiroshi Okada

Fuminori Kato

Kiyomitsu Yoshida

Norifusa Matsuo

Shinji Odawara

Hiroshi Sasaki

Hitoshi Nakayama

Yasunori Machida

Rie Higuchi

Ryuji Miyamoto

Taki Takenami

Mika Tanaka

Disclosed are a decoy peptide which is a partial peptide of ASYMMETRIC LEAVES1 (AS1), the decoy peptide being capable of interacting with &#x3b2;C1 encoded by a betasatellite of a virus belonging to the family Geminiviridae, a nucleic acid encoding the decoy peptide, an expression vector comprising the nucleic acid, a geminivirus disease control agent comprising the decoy peptide or the nucleic acid, a method for controlling a geminivirus disease using the geminivirus disease control agent, a transgenic plant into which the nucleic acid is introduced, and a method for reducing a disease symptom caused by a virus that comprises &#x3b2;C1 and belongs to the family Geminiviridae, using the nucleic acid. Also disclosed is a method for evaluating the degree of reduction in a disease symptom caused by a virus that comprises &#x3b2;C1 and belongs to the family Geminiviridae.

Peptide effective in control of geminivirus disease and use thereof

The present invention provides a preventive or therapeutic medicine for diabetes containing as an active ingredient a fused-heterocyclic compound of the formula (I') or its salt: [wherein G is CN, NO, COR, CHO, SONRRor CONRR; Ris a halogen atom, a &#x2014;O&#x2014;Rgroup or a &#x2014;S&#x2014;Rgroup; Ris a halogen atom, a &#x2014;O&#x2014;Rgroup (wherein Ris as defined above) or an amino group which may be substituted; and each of Rand Rwhich are independent of each other, is a hydrogen atom, a halogen atom or an alkyl group].

Preventive or therapeutic medicines for diabetes containing fused-heterocyclic compounds or their salts

Pyridazinone derivatives or their salts, processes for their production,

An imidazolidine derivative having the formula (I) or its salt: ##STR1## wherein X is an alkyl group which may be substituted, an alkenyl group which may be substituted, an alkynyl group which may be substituted, ##STR2## (in which each of R.sup.1, R.sup.2, R.sup.3 and R.sup.4 is independently a hydrogen atom or an alkyl group, R.sup.5 is an alkyl group which may be substituted with a halogen atom, a cycloalkyl group which may be substituted or a phenyl group which may be substituted, W is an oxygen atom or a sulfur atom, and each of k, l, m and n is independently 0 or 1, provided that (a) case where all of k, l and m are 0 at the same time and (b) case where m and n are 0 at the same time and R.sup.5 is an alkyl group which may be substituted with a halogen atom, are excluded), or ##STR3## group (in which each of R.sup.6 and R.sup.7 is independently a hydrogen atom or an alkyl group, each of R.sup.8 and R.sup.9 is independently an alkyl gorup, R.sup.10 is an alkyl group which may be substituted, an aryl group which may be substituted, a pyridyl group which may be substituted, an alkenyl group which may be substituted with a halogen atom or an alkynyl group which may be substituted with a halogen atom); Y is a 6-chloro-3-pyridyl group or a 2-chloro-5-thiazolyl group; Z is a hydrogen atom, an alkyl group or an acyl group; and j is an integer of from 0 to 2.

Imidazolidine derivatives, process for producing the same and pesticides

Growing community of inventors

Shiga, Japan

Masato Omatsu