Shiseido Company, Limited

Other

Hamamatsu-photonics K.k.

Fumio Eguchi

Masato Hatao

Yoshimasa Miura

Hiroshi Fukui

Eiichiro Yagi

Koji Kobayashi

Tomiyuki Nanba

Masaru Suetsugu

Kazuhisa Ohno

Mineyuki Yokoyama

Toshihiko Nakane

Masumi Koishi

Minoru Fukuda

Shigenori Kumagai

Hiroyuki Yokoyama

Yutaka Okunuki

Nobuhiko Ochiai

Fujihiro Kanda

Tadao Ohta

Toshihide Ebisawa

Susumu Takada

Takeshi Nawamura

Yoshio Yahata

Yusuke Hara

Yoshihiro Takiguchi

Sadaki Takata

Ichiro Iwai

Masayuki Shirao

Masako Naganuma

Osamu Moro

Kazuhisa Maeda

Toshihiro Tanaka

Kenji Yamaguchi

Motoki Ooguri

Hiroko Mizuno

An evaluation method for evaluating the ultraviolet protection effect of a measurement sample applied on a substrate includes measuring, at predetermined wavelength intervals, a change over time of a spectral transmission spectrum of the measurement sample within a predetermined wavelength range by irradiating light from a light source that includes ultraviolet light, visible light, and infrared light under a predetermined irradiation condition; establishing, based on the change over time of the spectral transmission spectrum, a correlation between a light irradiation time and an erythema effective dose per unit time, which is obtained by dividing an erythema effective dose of the measurement sample by an erythema effective dose per 1 MED; and calculating an in vitro rSPF predictive value for the measurement sample on the basis of a time until a cumulative erythema effective dose, which is obtained through time integration based on the correlation, reaches 1 MED.

Ultraviolet protection effect evaluation method, evaluation apparatus, and recording medium

A skin substitute membrane includes a surface on one side including a groove-shaped depressed portion and a planar portion, the depressed portion having a cross section having a chamfered V-letter shape, the surface having an arithmetic mean roughness Sa of more than or equal to 10 &#x3bc;m to less than or equal to 50 &#x3bc;m. The depressed portion has a width of more than or equal to 50 &#x3bc;m to less than or equal to 500 &#x3bc;m and a depth of more than or equal to 30 &#x3bc;m to less than or equal to 150 &#x3bc;m. A spectral transmittance for light of more than or equal to 290 nm to less than or equal to 400 nm in wavelength is more than or equal to 50% and less than or equal to 100%.

Skin substitute membrane, mold, and method of evaluating external preparation for skin

An ultraviolet radiation detector, detecting an ultraviolet radiation transmitted through or reflected from a measurement samplefrom a light beam including at least the ultraviolet radiation, is characterized by spectral meansfor spectrally splitting the ultraviolet radiation from the light beam and photodetection meansfor detecting the ultraviolet radiation spectrally split by the spectral means, the photodetection meansincluding a photoelectric surface detecting only the ultraviolet radiation and formed of an element selected from In, Ga, N, Al, O and Cs.

Ultraviolet radiation detector and apparatus for evaluating ultraviolet radiation protection effect

A method and apparatus for evaluating an ultraviolet radiation protection effect in a measurement sample is used for evaluating SPF (Sun Protection Factor). First, a temporal change of the spectral transmission spectrum in the measurement sample within a predetermined light wavelength range at predetermined wavelength intervals is measured. Second, a correlation between a light irradiating time and minimal erythema doses by predetermined lime intervals based on the temporal change of the spectral transmission spectrum is set. Third a predicted in vitro SPF in the measurement sample using a time until an accumulated minimal erythema dose that is obtained as a time integration of the minimal erythema doses based on the correlation obtained in the second step reaches 1 MED (Minimum Erythema Dose) is calculated.

Method, apparatus, program, and recording medium for evaluating ultraviolet radiation protection effect

The present invention provides an antioxidant and a whitening agent having high safety, and a external preparation for skin using the same. The antioxidant and whitening agent comprise, as an effective component, one or more extracts fromselected from the group consisting ofand. These extracts have a free radical capturing ability and are useful for suppressing skin oxidation and for preventing and improving skin aging. In addition, the extracts have a tyrosinase activity inhibiting action and can suppress the melanin generation. Since the fruit bodies of thesehave been used for edible purpose and have high safety, they can be used preferably for an external preparation for skin.

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The present invention provides an antioxidant and a whitening agent having high safety, and a external preparation for skin using the same. The antioxidant and whitening agent comprise, as an effective component, one or more extracts fromselected from the group consisting ofandThese extracts have a free radical capturing ability and are useful for suppressing skin oxidation and for preventing and improving skin aging. In addition, the extracts have a tyrosinase activity inhibiting action and can suppress the melanin generation. Since the fruit bodies of thesehave been used for edible purpose and have high safety, they can be used preferably for an external preparation for skin.

Antioxidant, whitening agent and external preparation for skin using the same

A method of preventing darkening of the skin or inhibiting melanization caused by the irradiation of the melanin monomers with long wavelength ultraviolet rays having a wavelength of 320-400 nm as well as a polymerization inhibitor of a biological dihydroxyindole compound comprising 3-O-ethyl ascorbic acid and an external skin treatment composition containing the same.

Method of preventing darkening of skin or inhibiting melanization of melenin monomer and polymerization inhibitor of biological dihydroxyindole compound

The present invention is an endermic liniment which characteristically contains a thiol compound and zinc oxide. An endermic liniment which can contain a thiol compound in a stable manner can be provided by blending in a thiol compound and zinc oxide.

Endermic liniment containing a thiol compound and zinc oxide

A magnesium aluminometasilicate coated composite powder which comprises magnesium aluminometasilicate, or magnesium aluminometasilicate and at least one other powder coated on a surface of a core powder and which is usable in, for example, a skin treatment agent, decodorant, and oral composition.

Magnesium aluminometasilicate coated composite powder and use thereof

A composite powder wherein an organic or inorganic core powder is substantially completely covered with one or more types of organic, inorganic, or metallic powders having an average particle size one-fifth or less of the average particle size of the above core powder by means of mixing and compression. The composite powder may be manufactured by mixing and compressing the above core powder and coating powder using a ball mill or other mixer charged with a ball shaped mixing medium of an average diameter of 5 mm or less. This composite powder may be used in, for example, skin treatment agent, makeup type cosmetics, sunburn preventing cosmetics, deodorants.

Composite powder and production process

Growing community of inventors

Yokohama, Japan

Masato Hatao