Seiko Epson Corporation

Nippon Steel Corporation

Konica Minolta, Inc.

Renesas Electronics Corporation

Vallourec & Mannesmann Oil & Gas France

Nippon Steel Sumitomo Metal Corporation

Toppan Printing Co., Ltd.

Sumitomo Metal Industries, Inc.

Konica Minolta Medical and Graphic, Inc.

Tohoku University

Tokico, Ltd.

Chugoku Marine Paints, Ltd.

Vallourec Oil and Gas France

Thyssenkrupp Electrical Steel Gmbh

Masaru Takahashi

Kazutoshi Takeda

Shuichi Yamazaki

Hiroyasu Fujii

Yuji Aoki

Yoshihiro Koizumi

Takeshi Iwamuro

Masahiro Karasawa

Taku Ishizawa

Yoshiyuki Ushigami

Yoshiaki Shimizu

Kunio Goto

Hitoshi Hayakawa

Takakazu Fukano

Ryuichi Imai

Satoshi Gocho

Takuya Matsumoto

Masato Yasuda

Shinichi Matsui

Hiroyuki Ito

Kensaku Takanashi

Hideki Gouda

Nobusato Morishige

Yoshinobu Goto

Keishi Matsumoto

Seiji Tojo

Akihito Matsumoto

Takeru Ichie

Takuya Owa

Takayuki Kamimura

Fuminobu Murakami

Hiroshi Satoh

Masahiro Yamamoto

Shinsuke Takatani

Masamichi Fujito

Ichiro Tanaka

Takashi Kataoka

Kohsuke Gonda

Shinya Yano

Noriaki Ohuchi

Akio Niu

Michihiko Iwamoto

Mamoru Sakugawa

Hideki Ochiai

Shohji Nagano

Ryutaro Yamagata

Yoshikatsu Yamamoto

Tomoya Suenaga

Yoshihiro Nakamura

Hiroki Hori

Atsushi Kijima

Hisao Tanaka

Satoshi Shinada

Shinji Yamamoto

Tadahiro Mizutani

Minoru Usui

Hidetoshi Kodama

Yasushi Nakano

Takahiro Naka

Fumiaki Takahashi

Hiroyuki Kawate

Nobuhito Takahashi

Kazuhiko Hara

Shuhei Harada

Eiichiro Watanabe

Hisashi Koike

Kazuo Hikida

Hideyuki Hamamura

Atsushi Yoshida

Yoshiaki Natori

Jun Shimazaki

Shunsuke Okumura

Izumi Iida

Hisatake Okada

Hisashi Mogi

Tesshu Murakawa

Masanari Kimoto

Yuichi Ozaki

Hideki Hoshino

Shigeo Nagasaku

Nobusato Kojima

Takayuki Kawakami

Mika Watanabe

Hiroyoshi Yashiki

Hideki Okumura

Takeshi Isoda

Takashi Akase

Kazumi Mizukami

Yoshihiro Arita

Isamu Sejimo

Kunihiro Fukui

Masato Mizokami

Takahito Mizumura

Hirotoshi Tada

Soichi Kobayashi

Tamotsu Toki

Takuji Aimiya

Motohiro Takeda

Kazuhito Imai

Sota Yamamoto

There is provided a non-oriented electrical steel sheet that includes a base metal steel sheet and an insulating coating film that is formed on a surface of the base metal steel sheet, wherein the insulating coating film mainly contains metal phosphate, organic resin, and water-soluble organic compound, the water-soluble organic compound has an SP value that is within a range of 10.0 to 20.0 (cal/cm), the metal phosphate contains aluminum and zinc as metallic elements, and when measurement by an X-ray photoelectron spectroscopy is performed from a surface of the insulating coating film in a thickness direction of the non-oriented electrical steel sheet, a depth at which a strength of a 2p peak of zinc reaches a maximum is present closer to the surface side than a depth at which a strength of a 2p peak of aluminum reaches a maximum, and a maximum value of the strength of the 2p peak of zinc is 1 to 20 times a strength of the 2p peak of aluminum at the depth at which the strength of the 2p peak of zinc reaches a maximum.

Non-oriented electrical steel sheet and surface treatment agent for non-oriented electrical steel sheet

There is provided a non-oriented electrical steel sheet that includes a base metal steel sheet and an insulating coating film that is formed on a surface of the base metal steel sheet, wherein the insulating coating film mainly contains metal phosphate, organic resin, and water-soluble organic compound, the metal phosphate contains at least aluminum as a metallic element, the organic resin has an SP value being within a range of 18.0 (MPa)or more to less than 24.0 (MPa), the water-soluble organic compound has an SP value being within a range of 19.0 (MPa)or more to less than 35.0 (MPa), and when measurement by X-ray diffractometry is performed on the insulating coating film, a degree of crystallinity of aluminum phosphate calculated from a peak from the metal phosphate is within a range of 0.5 to 5.0%.

Non-oriented electrical steel sheet

Disclosed herein is a method including: acquiring one or more pieces of information including information about expression status of a specific biomarker in a lesion collected from a human by using a laboratory animal transplanted with the lesion; and using the information to estimate therapeutic efficacy through analysis.

Method for estimating therapeutic efficacy

An grain-oriented electrical steel sheet according to the present invention includes: a base steel sheet; an oxide layer that is formed on the base steel sheet and is formed of amorphous SiO; and a tension-insulation coating that is formed on the oxide layer. The base steel sheet includes, as a chemical composition, by mass %, C: 0.085% or less, Si: 0.80% to 7.00%, Mn: 1.00% or less, acid-soluble Al: 0.065% or less, Seq represented by S+0.406·Se: 0.050% or less, and a remainder consisting of Fe and unavoidable impurities. FWHM that is a half width of a peak of cristobalite type aluminum phosphate obtained by X-ray diffraction satisfies (i) when X-ray diffraction is performed using a Co-Kα excitation source, a half width (FWHM-Co) of a peak appearing at 2θ=24.8° is 2.5 degree or less, or (ii) when X-ray diffraction is performed using a Cu-Kα excitation source, a half width (FWHM-Cu) of a peak appearing at 2θ=21.3° is 2.1 degree or less.

Grain-oriented electrical steel sheet

The wound core of the present invention has at least one arbitrary bent regionA, in a plurality of corner portions (), in which the corner portion () bulges outward to confine the magnetic flux flowing in the wound core so that the angle θ formed by the straight line PQ and the straight line PR satisfies 23°≤θ≤50°.

Wound core

A non oriented electrical steel sheet consists of a silicon steel sheet and an insulation coating. The silicon steel sheet contains Si, Al, and Mn as chemical composition, and an alignment degree to {5 5 7}<7 14 5> orientation in a central area along a thickness direction of the silicon steel sheet is 12 to 35.

Non oriented electrical steel sheet and method for producing thereof

Grain-oriented electrical steel sheet excellent in magnetic properties and excellent in adhesion of a primary coating to the steel sheet is provided. The grain-oriented electrical steel sheet is provided with a base steel sheet having a chemical composition containing C: 0.005% or less, Si: 2.5 to 4.5%, Mn: 0.050 to 1.000%, a total of S and Se: 0.005% or less, sol. Al: 0.005% or less, and N: 0.005% or less and having a balance of Fe and impurities and a primary coating having MgSiOas a main constituent formed on a surface of the base steel sheet. A peak position of Al emission intensity obtained when conducting elemental analysis by glow discharge spectrometry from a surface of the primary coating in a thickness direction is present in a range of 2.0 to 12.0 μm from a surface of the primary coating to the thickness direction. A sum of perimeters of the Al oxides at the peak position of Al emission intensity is 0.20 to 1.00 μm/μm, and a number density of Al oxides is 0.02 to 0.20/μm.

Grain-oriented electrical steel sheet and method for manufacturing same and annealing separator

Provided is a grain-oriented electrical steel sheet including a base steel sheet, an intermediate layer which is disposed in contact with the base steel sheet and mainly includes silicon oxide, and an insulation coating which is disposed in contact with the intermediate layer and mainly includes phosphate and colloidal silica, in which the base steel sheet contains predetermined chemical composition, BN having an average particle size of 50 to 300 nm is present, when an emission intensity of B is measured using glow discharge emission analysis, predetermined conditions are satisfied, and a ratio of a major axis to a minor axis of BN is 1.5 or less.

Grain-oriented electrical steel sheet having excellent insulation coating adhesion without forsterite coating

A non oriented electrical steel sheet consists of a silicon steel sheet and an insulation coating. The silicon steel sheet includes an internally oxidized layer containing SiOin a surface thereof, an average thickness of the internally oxidized layer is 0.10 to 5.0 μm, and a Vickers hardness in the internally oxidized layer is 1.15 to 1.5 times as compared with a Vickers hardness in a thickness central area.

Non oriented electrical steel sheet

The grain-oriented electrical steel sheet according to the present invention is a grain-oriented electrical steel sheet having a base steel sheet (), an intermediate layer () disposed to be in contact with the base steel sheet (), and an insulation coating () disposed to be in contact with the intermediate layer (), and the grain-oriented electrical steel sheet includes a surface of the base steel sheet () having a groove (G) which extends in a direction intersecting a rolling direction of the base steel sheet (), in which in a cross-sectional view of a plane parallel to the rolling direction and a sheet thickness direction of the base steel sheet (), when a region between end portions of the groove (G) is defined as a groove part (R), an average thickness of the intermediate layer () of the groove part (R) is 0.5 times or more and 3.0 times or less an average thickness of the intermediate layer () other than the groove part (R), and an area ratio of voids in the insulation coating () of the groove part (R) is 15% or less.

Grain-oriented electrical steel sheet and method for manufacturing the same

The present invention relates to a method for detecting an antibody-drug-conjugate and relates to a method for determining the efficacy of an antibody-drug-conjugate with high accuracy by a quantitative technique for identifying an expression level of a target molecule in a target cell of the antibody-drug-conjugate and interactions therebetween. According to the method, visualizing a drug and an antibody, or components of an antibody-drug-conjugate, by immunostaining with a phosphor integrated dot enables detection of the antibody-drug-conjugate and the components.

Method for detecting constituent component of antibody-drug conjugate

Grain-oriented electrical steel sheet excellent in magnetic properties and excellent in adhesion of a primary coating to the steel sheet is provided. The grain-oriented electrical steel sheet is provided with a base steel sheet having a chemical composition containing C: 0.005% or less, Si: 2.5 to 4.5%, Mn: 0.050 to 1.000%, a total of S and Se: 0.005% or less, sol. Al: 0.005% or less, and N: 0.005% or less and having a balance of Fe and impurities and a primary coating having MgSiOas a main constituent formed on a surface of the base steel sheet. A peak position of Al emission intensity obtained when conducting elemental analysis by glow discharge spectrometry from a surface of the primary coating in a thickness direction is present in a range of 2.0 to 12.0 &#x3bc;m from a surface of the primary coating to the thickness direction. A sum of perimeters of the Al oxides at the peak position of Al emission intensity is 0.20 to 1.00 &#x3bc;m/&#x3bc;m, and a number density of Al oxides is 0.02 to 0.20/&#x3bc;m.

A grain-oriented electrical steel sheet has a steel sheet and an insulating coating which is formed on a surface of the steel sheet. In the insulating coating, a metal phosphate and a colloidal silica are contained, the colloidal silica is contained in an amount of 20 to 150 parts by mass with respect to 100 parts by mass of the metal phosphate, one or more kinds of fine particles selected from the group consisting of silicon carbide, silicon nitride, aluminum nitride, boron nitride, sialon, and cordierite are further contained in an amount of 0.5 to 7 parts by mass with respect to 100 parts by mass of the metal phosphate, an average particle size of the fine particles is 0.3 to 7.0 &#x3bc;m, crystallized ratio of the metal phosphate is 2% to 40%, and chromium is not contained.

A grain oriented electrical steel sheet includes: a base steel sheet; a glass film which is arranged in contact with the base steel sheet; and an insulation coating which is arranged in contact with the glass film and which includes a phosphate and a colloidal silica as main components. The base steel sheet includes the predetermined chemical composition. A BN whose average particle size is 50 to 300 nm is included at a predetermined number density in a region which is from an interface between the glass film and the insulation coating till 5 &#x3bc;m toward the base steel sheet in a depth direction. A B emission intensity obtained inside the glass film is more than a B emission intensity obtained inside the base steel sheet, when a B emission intensity is measured from a surface of the insulation coating by a glow discharge emission spectroscopy.

Grain oriented electrical steel sheet

A grain oriented electrical steel sheet includes: a base steel sheet; a lower layer which is arranged in contact with the base steel sheet; and an insulation coating which is arranged in contact with the lower layer and which includes a phosphate and a colloidal silica as main components. The base steel sheet includes the predetermined chemical composition and includes a B compound whose major axis length is 1 to 20 &#x3bc;m and whose number density is 1&#xd7;10 to 1&#xd7;10pieces/mm. The lower layer is a glass film which includes a forsterite as main component or an intermediate layer includes a silicon oxide as main component.

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Tokyo, Japan

Masaru Takahashi