Ajinomoto Co., Ltd.

Masaru Okutsu

Naohiko Yasuda

Kahei Takase

Takashi Meguro

Masabumi Yasunami

Katsumi Suzuki

Toru Nakamura

Nobuo Kato

Chikahiko Eguchi

Takao Kida

Yoshiteru Hirose

Hiroshi Mizuno

Osamu Hiwatashi

Hisao Iwagami

Kunio Torii

Takaaki Kobayashi

Toru Mimura

Ichiro Takase

Teruaki Nakamiya

Akira Shinji

Azulene derivatives of the following formula ##STR1## wherein R.sup.1 stands for an alkyl group of 1 to 3 carbon atoms, R.sup.2 stands for an alkyl group of 1 to 3 carbon atoms, and R.sup.3 is at the 5- or 6-position and stands for an alkyl group of 1 to 6 carbon atoms, an aryl group of 6 to 9 carbon atoms or an aralkyl group of 7 to 10 carbon atoms; have antihyperlipidemic activity. Many of the compounds are also novel per se.

Azulene derivatives and pharmaceutical compositions containing them

Azulene derivatives of the following formula ##STR1## wherein R.sup.1 stands for an alkyl group of 1 to 3 carbon atoms, R.sup.2 stands for an alkyl group of 1 to 3 carbon atoms, and R.sup.3 is at the 5- or 6- position and stands for an alkyl group of 1 to 6 carbon atoms, an aryl group of 6 to 9 carbon atoms or an aralkyl group of 7 to 10 carbon atoms; have antihyperlipidemic activity. Many of the compounds are also novel per se.

An azulene derivative capable of exerting a hypocholesterolemic effect on a mammal which is represented by the formula ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and are selected from the group consisting of hydrogen, C.sub.1 -C.sub.12 alkyl groups and C.sub.2 -C.sub.12 alkenyl groups.

Azulene derivatives and their use as hypocholesterolemics

The invention relates to imidazolecarboxylic acid derivatives of penicillins and cephalosporins, which are especially useful for the treatment of Pseudomonas aeruginosa-derived infections in humans and other animals.

Imidazolecarboxylic acid derivatives

An imidazoledicarboxylic acid derivative having the following formula: ##STR1## wherein X is a group selected from the group consisting of hydrogen atom and hydroxyl group. The compounds are useful as antibiotics.

Imidazoledicarboxylic acid derivative

Compounds having the following formula: ##STR1## wherein X is a radical selected from the group consisting of hydrogen, halogen, hydroxy, mercapto, methyl and amino.

Imidazoledicarboxylic acid substituted cephalosporin derivatives

A herbicidal composition comprising a herbicidal amount of an active compound selected from the group consisting of acid addition salts of higher alkyl esters of amino acids, acid addition salts of N-lower alkyl substitution products of said esters and quaternary ammonium salts of N-lower alkyl substitution products of said esters, and a diluent or carrier, and a method for controlling weeds using said herbicidal composition.

Herbicidal composition of amino acid higher alkyl ester type and method

Method for controlling weeds with amino acid higher alkyl esters

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Yamato, Japan

Masaru Okutsu