Ube Nitto Kasei Co., Ltd.

Research Development Corporation of Japan

Japan Medical Supply Co., Ltd.

Masao Okada

Kazuhiko Sakai

Haruo Kimura

Yoshito Ikada

Masayoshi Ono

A synthetic vascular prosthesis comprises a hollow tubular base member having a multitude of continuous pores and formed of an elastomer material, and a hydrogel layer formed on the inner surface of the base member. The hydrogel layer is partly embedded in the inner portion of the base member at the pores, thereby permitting anchoring adhesion between the hydrogel layer and the base member. A method for manufacturing the synthetic vascular prosthesis is also disclosed, in which the formation of pores in the base member is effected by two separate steps and the hydrogel layer is formed after formation of an inner porous portion of the base member.

Method for manufacturing a synthetic vascular prosthesis

Synthetic vascular prosthesis

A molten thermoplastic resin is extruded in the form of a double-layer cylindrical hollow film with the two film layers being interconnected with each other by a number of spaced legs and is then immediately passed through an annular gap defined by annular side walls of inner and outer vessels in such a manner that the two film layers are in contact with the respective side walls defining the gap. Coolant is supplied to the inner and outer vessels and overflows above the side walls to bring the coolant into contact with the resin. The level of the coolant overflowing above both side walls is adjusted to be equal and also to have a liquid pressure on the extruded resin balanced with a gas pressure supplied in between the two film layers and the legs of the extruded resin.

Method and apparatus for forming double-layer hollow film

Growing community of inventors

Gifu, Japan

Masao Okada