Simpson Biotech Co., Ltd

Lead Chemical Company, Limited

Mitsui Norin Co., Ltd.

Masao Hattori

Chia-Chin Sheu

Ali El-Halawany

Megumi Mizuno

Yukihiko Hara

Masao Mori

Haruo Saito

Hideo Nemoto

Naoiki Yamamoto

Coolin Yang

The present invention relates to compounds from. The present invention also relates to a composition and a method for treating or prophylaxis of hepatitis C virus (HCV) or human immunodeficiency virus (HIV) infection.

[object Object]

The present invention relates to compounds from mycelium of. The present invention also relates to a composition and a method for treating or prophylaxis of hepatitis C virus (HCV) infection.

The present invention relates to a compound derived from mycelium of. The present invention also relates to the composition or mycelium comprising the compounds of the invention. The composition of the invention decreases systolic blood pressure and increases high density lipoprotein.

The present invention relates to novel compounds fromand their use.

The invention relates to polysaccharide extracted fromand the method for preparing the polysaccharide. The invention also relates to compositions and methods for hepatoprotective effect.

The present invention relates to novel compounds fromand the use thereof.

An antiviral preparation comprising as an active ingredient, a phorbol derivative of formula 1: wherein is Ris &#x2014;(CH)X(CH)CH, &#x2014;(CH)X(CH)YCH, &#x2014;CO(CH)CHor &#x2014;(CH)CHRis &#x2014;CO(CH)CH, R, Rand Rare hydrogen atom, or an aliphatic or aromatic carboxylic acid residue, X and Y are O or S, and each of a-f and n is a number, and having a specific safety index S.I.=CC/ECof 10 or more wherein ECmeans a concentration at which HIV-1 induced cytopathogenic effect (CPE) in MT-4 cell is inhibited by 50%, and CCmeans a concentration at which survival of MT-4 cell in a cell proliferation test is reduced by 50%. These preparations are particularly effective for human immuno-deficiency virus (HIV).

Compounds and preparations having antiviral effect

The present invention relates to novel mixture and maleic and succinic acid derivatives from mycelium ofand the medical use thereof. The present invention relates to the composition or mycelium comprising the compounds of the invention.

An antiviral agent comprising as an active ingredient a phorbol derivative of formula (I):

Phorbol derivatives having antivirus activity

An anti-dental plaque agent is composed primarily of a tea-leaf polyphenol or polyphenols selected from the group consisting of epigallocatechin gallate or its isomer, epicatechin gallate or its isomer, epigallocatechin or its isomer, epicatechin or its isomer, (+)catechin or its isomer, free type theaflavin, theaflavin monogallate A, theaflavin monogallate B and theaflavin digallate.

Growing community of inventors

Toyama, Japan

Masao Hattori