Panasonic Corporation

Panasonic Healthcare Co., Ltd.

Phc Holdings Corporation

Panasonic Healthcare Holdings Co., Ltd.

Izumi Products Company

Masanori Tanaka

Takashi Miki

Hirotaka Tanaka

Hiroshi Saiki

Fumihisa Kitawaki

Fusatoshi Okamoto

Masahiro Johno

Yoshiyuki Fujii

Takuya Suzuki

Chizu Asahara

Kouji Nino

Miho Okano

This substrate for sample analysis, which transfers a sample-containing liquid by means of rotation and analyzes a specific substance in a sample, is provided with: a space which holds the sample-containing liquid in a substrate having a rotary shaft; a reaction chamber having an inlet and an outlet connected to the space; and a dried reagent disposed in the space of the reaction chamber. The space has a first end and a second end spaced apart from each other in a circumferential direction. The inlet and the outlet are arranged at the first end and the second end, respectively. The space has a capillary portion, and a first non-capillary portion which is connected to the capillary portion, is located at the second end, has an opening, and extends in a radial direction. The outlet is connected to the outer peripheral side of the first non-capillary portion.

Substrate for sample analysis

Hemoglobin in a sample solution is quickly and reliably denatured; at the same time, quick and accurate measurement of hemoglobin and a hemoglobin derivative is realized. In a method for measuring hemoglobin and a hemoglobin derivative, and a reagent composition, a measurement kit, an analysis device, and an analysis system used in the method, a sample solution containing a blood component is treated with a nonionic surfactant, an oxidizing agent, and a metal salt to denature hemoglobin in the sample solution to measure the hemoglobin, and thereafter the amount of a hemoglobin derivative in the sample is measured by an immunological method using an antibody specifically binding to a denatured site of the denatured hemoglobin derivative.

Method for producing agglutinating reagent, agglutinating reagent or product produced thereby, and method for measuring analysis object using the same, and test kit and analysis device

An analysis device includes: a separation cavityfor separating a test liquid into a solution component and a solid component by using a centrifugal force; a higher specific gravity component quantitative cavityfor holding a portion of the separated solid component which has been transferred; a sample solution overflow cavityarranged between the higher specific gravity component quantitative cavityand the separation cavityand connected to a connecting channelfor transporting the sample liquid from the separation cavity; and a capillary cavityformed in the separation cavityfor temporarily holding a separated solution component (blood plasma) in the separation cavity. A blood plasma componentremaining in the separation cavityis trapped by the capillary cavity

Analysis device and method using the same

A sample solution including blood components is processed with a denaturalization reagent comprising a nonionic surface-activating agent and an oxidizing agent to denaturalize a hemoglobin derivative in the sample solution, and thereafter, an immunoassay is performing utilizing an antibody that is specific to a denaturalized site of the hemoglobin derivative to measure the amount of the hemoglobin derivative in the sample. Therefore, when performing assay of hemoglobin derivative, denaturalization of hemoglobin can be performed speedily and reliably while minimizing adverse effects of the denaturalization reagent on immune reaction.

Hemoglobin derivative measurement method, and reagent composition, measurement kit, analysis device and analysis system for use in the method

An analysis device includes a separation chamber, a holding channel, a mixing chamber connected to the holding channel, an overflow channel connected between the holding channel and the separation chamber, a sample overflow chamber into which a sample solution remaining in the separation chamber is discharged, and a joint channel connecting the separation chamber and the sample overflow chamber. After the separated solution component fills the overflow channel with priority, a separated solid component is transferred to the holding channel via the overflow channel, and a predetermined amount of the solid component is measured. The solid component in the holding channel is transferred to the mixing chamber by a centrifugal force, and simultaneously, the sample solution remaining in the separation chamber is discharged to the sample overflow chamber by the siphon effect of the joint channel.

Analysis device and an analysis apparatus using the analysis device

Method for measurement of hemoglobin and hemoglobin derivative, and measurement kit

An analysis device comprises a separation chamber for separating a sample solution into a solution component and a solid component, a holding channel, a mixing chamber connected to the holding channel, an overflow channel connected between the holding channel and the separation chamber, a sample overflow chamber into which the sample solution remaining in the separation chamber is discharged, and a joint channel connecting the separation chamber and the sample overflow chamber. After the separated solution component fills the overflow channel with priority, the separated solid component is transferred to the holding channel via the overflow channel, and a predetermined amount of the solid component is measured. The solid component in the holding channel is transferred to the mixing chamber by a centrifugal force, and simultaneously, the sample solution remaining in the separation chamber is discharged to the sample overflow chamber by the siphon effect of the joint channel.

Growing community of inventors

Ehime, Japan

Masanori Tanaka