Nisshin Flour Milling Co., Ltd.

Lederle (Japan), Ltd.

Masanori Sugita

Toshihiro Takahashi

Haruo Seto

Noboru Otake

Koichi Nakamaru

Hitoshi Inoue

Masato Horigome

Masao Nagase

Kenichi Momose

Tetsuo Sasaki

Chikako Suzuki

Shinji Nagai

Kouichi Katsuyama

Yoshiyuki Tahara

Shigeru Hiramoto

Ikuo Kishi

Osamu Ogawa

Noriyoshi Sueda

Yohei Natori

Disclosed are indole derivatives of formula (I) ##STR1## wherein X and Y each independently represent H or --CH.sub.2 CH.sub.2 R; R represents pyridyl or substituted amino of NR.sub.1 R.sub.2 ;

Indole derivatives

Disclosed are indole derivatives of formula (I) ##STR1## wherein X and Y each independently represent H or --CH.sub.2 CH.sub.2 R;

Disclosed are indole derivatives of formula (I) ##STR1## wherein Y represents H, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkoxy or halogen;

Indole derivatives and anti-ulcer compositions thereof

A pharmaceutical oil-in-water type microemulsion having an action of potentiating the activities of anti-cancer agents, said micro-emulsion comprises

Anti-cancer activity potentiator

A pharmaceutical oil-in-water type microemulsion having an action of potentiating the activities of anti-cancer agents, said micro-emulsion comprises fine particles of a vegetable oil or a triglyceride of a medium-chain fatty acid having 8 to 12 carbon atoms containing 0.1 to 10% (w/v) of N-solanesyl-N,N'-bis(3,4-dimethoxybenzyl)ethylenediamine malate of formula (I) below, ##STR1## an aqueous medium, and, 0.05 to 25% (w/v) of a physiologically acceptable phospholipid for dispersing said fine particles in said aqueous medium.

Mycotrienin-related compounds called the T-23-X, -XI, -XII, -XIII and -XIV. These compounds are isolated and characterized by structural formula and other identifying data. They are useful in the treatment of tumors.

Mycotrienin-related compounds

Mycotrienin-related compounds called the T-23-VIII and T-23-IX substances. These substances are isolated and characterized by structural formula and other identifying data. These substances are useful in the treatment of tumors.

The disclosure describes a microbiological process for the preparation of mycotrien-related compounds. The compounds are isolated and characterized by structural formula and other identifying data. The compounds are useful in the treatment of tumors.

Growing community of inventors

Saitama, Japan

Masanori Sugita