Pentax Corporation

Other

Asahi Kogaku Kogyo Kabushiki Kaisha

Hoya Corporation

Katakura Chikkarin Co., Ltd.

Masanori Nakasu

Asako Matsushima

Akira Yamamoto

Tsuyoshi Ishikawa

Toshio Matsumoto

Katsumi Kawamura

Satoshi Ojima

Keita Abe

Ichiro Ono

Yoshiyuki Ogawara

Yoshie Tominaga

Hajime Yamada

Masahiro Kohketsu

Takahiro Fukuhara

Tunenori Takei

Takatoshi Kudou

Tsutomu Takahashi

Kaoru Arai

Makoto Otsuka

A porous calcium phosphate ceramic body comprising a substrate, and three-dimensional nanotunnel layersformed on wall surfaces of the substrate, the three-dimensional nanotunnel layershaving pluralities of three-dimensionally connected nanotunnels

Porous calcium phosphate ceramic and method for producing same

A method of manufacturing a powder, by which it is possible to adjust the strength of the obtained powder is provided. The manufacturing method of a powder involves a step of preparing a slurry containing agglomerated particles of a synthetic material which is produced by reacting a first material and a second material under agitation, and a step of drying the slurry to obtain a powder of the synthetic material. The method has a feature that the particle size of the agglomerated particles is adjusted by, in the step of preparing a slurry, controlling agitation power for agitating the slurry. In the step of preparing a slurry, it is preferable that the slurry is initially agitated at a first agitation power, and at the time when the viscosity of the slurry approaches its maximum value, or at the time when the pH value of the slurry reaches the vicinity of the isoelectric point of the synthetic material, the agitation power is lowered from the first agitation power to a second agitation power. Further, it is preferable that before or after the completion of the reaction of the first material and the second material, the agitation power is increased from the second agitation power to a third agitation power.

Method of manufacturing powder

A prosthetic filler for a living body having excellent storage properties and handlability is disclosed. The prosthetic filler includes calcium phosphate granules and porous small chips made of an organic material for binding these calcium phosphate granules to each other. The prosthetic filler is made by mixing the calcium phosphate granules and the small chips of the organic material. When the prosthetic filler is used for a living body, it is added with water, and then they are kneaded to become a paste state. Thus obtained paste state prosthetic filler is injected into a bone defect site or the like to restore it.

Prosthetic filler for a living body and method of manufacturing the prosthetic filler

A method of manufacturing a ceramic composite comprises the steps of preparing at least two ceramics bodies to be bonded together, each of the at least two ceramics bodies having a bonding surface; preparing a slurry in which primary particles of a bonding ceramic are dispersed; applying the slurry to the bonding surface of at least one of the ceramic bodies to be bonded; and sintering the ceramic bodies between which the slurry has been interposed to bond them. In this method, the bonding ceramic in the slurry is preferably constituted from the same ceramic starting material as that of the at least one of the ceramic bodies to be bonded. In this way, it becomes possible to manufacture, with a simple technique, a ceramic composite having a required strength and excellent biocompatibility and biosafety.

Ceramic composite and manufacturing method thereof

A method for forming an implant having a desired shape includes the steps of (a) forming a layer of ingredient powder having a predetermined thickness composed of an ingredient powder, and (b) applying an reactant liquid to the layer in accordance with the desired shape of the implant, portions of the ingredient powder reacting with the reactant liquid being hardened. The above steps are repeated to stack a plurality of the layers having hardened portions, respectively, to form a three-dimensional implant formed by a stack of the hardened portions of the layers of the ingredient powder. The ingredient powder is a powder including at least one of a-tricalcium phosphate and tetracalcium phosphate, and a Ca/P ratio of the powder is within a range of 1.40 through 2.0.

Implant forming method

A sustained release drug carrier comprises a ceramic composite which is formed by bonding a plurality of ceramic bodies together, and drugs impregnated into the ceramic composite. A method of manufacturing the sustained release drug carrier comprises the steps of: (i) preparing ceramic bodies to be bonded together, each of the ceramic bodies having a bonding surface; (ii) preparing a slurry in which primary particles of a bonding ceramics are dispersed; (iii) applying the slurry to the bonding surface of at least one of the ceramic bodies to be bonded; (iv) sintering the ceramic bodies between which the slurry has been interposed to bond them together, to obtain a ceramic composite; and (v) impregnating a drug into the obtained ceramic composite. According to the structure and method described above, it is possible to provide a sustained release drug carrier whose drug release properties can be controlled and which is capable of exhibiting better drug release action suitable for the application sites, type of drugs to be carried, and the like.

Sustained release drug carrier, and method of manufacturing sustained release drug carrier

A prosthetic bone material comprising a bonded and sintered product of granules of calcium phosphate compound having a particle size of at least 100 &mgr;m, each of the granules being bonded with particulates of calcium phosphate compound having a particle size of about 1 to 40 &mgr;m, in which the granules are bonded to each other while retaining their original shape, and their bonding strength is a level sufficient to maintain their own shape when the bonded and sintered product is disintegrated, produced by mixing the granules and the particulates, followed by firing the mixture at a temperature of about 800 to 1,200&deg; C.

Prosthetic bone material and process for the production of the same

An artificial socket comprising a composite body of a calcium phosphate compound and an in vivo-absorptive polymeric material. The artificial socket is embedded and secured in the pelvis side of the artificial hip joint. The socket has a configuration of a semi-spherical shell body, and the thickness thereof is thinner than that of a conventional artificial socket and the inner diameter thereof is substantially the same as that of a real socket in a human bone. An artificial hip joint using the artificial socket and a fixing screw suitable for the fixation of the socket in the pelvis are also disclosed.

Artificial socket, screw for fixing artificial socket and artificial hip

Growing community of inventors

Tokyo, Japan

Masanori Nakasu