Nipro Corporation

Nissho Corporation

Hoechst Japan Limited

Masanobu Iwasa

Minoru Honda

Koji Ikeda

Hitoshi Futagawa

Toshihiro Kikuchi

Yukihiro Yabe

Masaki Ikenoue

Mitsuru Hasegawa

Shigeki Tanaka

Teruhisa Hirobe

Takashi Asai

Yoshihisa Murai

Kenji Omori

Ryohei Namba

Noriyoshi Yamamoto

Tadatoshi Uchida

Hidero Kato

Tetuzi Miyamoto

Michiro Abe

Ryohei Nanba

Ryouji Komatsu

Cap for syringe

Provided is a vial rubber stopper using multiple types of rubber to prevent the vial rubber stopper from being scraped and from sticking to a presser plate. The vial rubber stopper includes: a cap portion having a flange; a piercing area formed to have a recess at a top surface of the cap portion and configured to traverse longitudinally the cap portion in an axial direction from the recess to a bottom surface of the cap portion; and a leg portion formed on the bottom surface of the cap portion in a way of extending downward and located outside the piercing area with respect to an axial center of the cap portion. The piercing area is formed of rubber having rubber hardness from 20 to 35, and the top surface other than the recess of the cap portion is formed of rubber having rubber hardness from 58 to 90.

Vial rubber stopper

A plunger for a syringe, in which a plunger rod can be prevented by a simple structure from unavoidably falling out of place. The plunger for a syringe includes the plunger rod and a gasket. The gasket is closed at its upper end and has an inner space, and an opening having a diameter smaller than the diameter of the inner space is provided in the lower end of the gasket. The plunger rod has a collar installed at the tip of the plunger rod. When the collar is positioned in the inner space of the gasket, the plunger rod and the gasket are freely movably fitted together without intimate contact between them.

Syringe plunger with one piece hollow gasket and plunger rod

The prefilled syringe filled with a drug in advance, leaking of liquid from the cap is prevented, gas barrier properties are given to the whole of the barrel filled with the drug and the shoulder section so that degradation of the drug is prevented, permeation of microbial contaminants is prevented to a high extent, and efficiency of packing as a compact container can be increased. The prefilled syringe includes a guard-shaped extension projecting from the outer periphery of a shoulder section of the syringe barrel on the nozzle side, and a range from a part where a gasket of the plunger is positioned on the outer surface of the syringe barrel filled with the drug to the guard-shaped extension is covered with barrier packaging.

Prefilled syringe

A medicine bag, which includes a bag body having a medicine storage chamber that stores a medicine in such a way that the medicine is visually confirmed through a light-transmission portion provided in at least one part of the bag body, the bag body having a weak seal portion that divides the medicine storage chamber into a plurality of division spaces, and the sealing of the weak seal portion adjacent to a specific division space being removed by increasing the internal pressure of that division space, including: a cover sheet which is peelably attached to the bag body; and a requisitely-used portion which is used in the process shortly before the medicine is administered, in which the cover sheet includes: a light-shielding portion which shields from the light the medicine stored in at least one division space by covering a predetermined part of the light-transmission portion; and a continuously-formed portion which is continuously formed in the light-shielding portion and is placed so that the requisitely-used portion is prevented from being used with the cover sheet kept attached.

Medicine bag

A holder comprises a basehaving an inclined planeincreased in height from a distal end thereof to the proximal end thereof; air releasing meansprovided on the proximal end of the baseand closing meansfor closing an opening Bof a flexible container set on the base. The closing meanscomprises a pressure assemblyhaving closing barsextending in the direction perpendicular to the longitudinal axis X of the base,and a lever. The pressure assemblyis adapted to doubly seal the opening Bof the flexible container B when the leveris turned over toward the distal end of the base

Holder for freeze-drying of drug solutions

A flexible and dual-chambered container includes a first frontal sheet fusion bonded to a first rear sheet to define a first chamber for containing, for example, a medical liquid. The first frontal sheet is a flexible and transparent sheet for intercepting water, moisture, and oxygen gas. The first rear sheet is a flexible composite sheet composed of aluminum foil and a water-absorbing stratum. A second frontal sheet is fusion bonded to a second rear sheet to define a second chamber for containing, for example, a medical liquid. The second frontal and rear sheets are joined to the first frontal and rear sheets so that the first and second chambers are isolated by a breakable or weak seal. An opaque and flexible cover sheet composed of aluminum foil is removably disposed on the first frontal sheet. When the weak seal is broken by manually compressing the second chamber, the first and second chambers are brought into liquid communication. Any residual amount of water or vapor can be eliminated from the container during manufacturing so that the dry drug contained therein is protected from oxygen, water, and light beams.

Flexible dual-chambered container

A solvent container to be used in combination with a drug container or vial, which comprises a flexible container body containing a solvent therein and having a mouth covered with a self-sealing member, a guide capsule having an open end sealed by a sealing member and being removably mounted on the mouth of the container body; and a double-pointed hollow needle having a sharp piercing edge at each end and being slidably arranged in the guide capsule to constitute a means for communicating the container body with the drug vial in cooperation with the guide capsule.

Solvent container with a connecter for communicating with a drug vial

A fluid container comprises a drug container, a deformable solvent container, a double-pointed hollow needle having a sharp piercing edge at each end and being arranged between the drug container and the solvent container, a guide capsule with a cap rotatably mounted thereon, and a means for converting rotary motion of the cap to a linear motion of the drug container to push the drug container toward the solvent container in cooperation with the cap and the guide capsule so that a fluid communication is made between two containers through the needle.

Fluid container

A syringe-needle-like nozzle for tissue adhesive comprising a hub and a deformable cannula without a bevel, the cannula being made of high-ductile metallic material for medical use and fixed in the hub. The nozzle of the present invention is satisfactorily applicable in tissue adhesive injection to complex regions or small regions in organism. Further, there can be carried out the injection of tissue adhesive to different regions by means of suitable deformation of the nozzle shape.

Growing community of inventors

Osaka, Japan

Masanobu Iwasa