Nissan Chemical Industries Limited

Nissan Chemical Corporation

Tohoku Techno Arch Co., Ltd.

Other

Dainippon Sumitomo Pharma Co., Ltd.

Masami Kozawa

Shinsuke Tadokoro

Kenji Suzuki

Toshimasa Hamada

Yoshiharu Iwabuchi

Masaki Tomizawa

Yusuke Sasano

Masatoshi Shibuya

Noriaki Nagahama

Ryoji Noyori

Yasunobu Someya

Takao Ikariya

Hiroyuki Wakayama

Isao Hashiba

Kunihiko Murata

Ryuta Mizuochi

Takeshi Ohkuma

Kiyotomo Seto

Hisato Hayashi

Yuki Endo

Hideyuki Ikehira

Hideki Musashi

Takashi Oda

Daisuke Hatanaka

Yoshinobu Yanagawa

Kenichi Tokunaga

Keisuke Morodome

Toru Yokozawa

Eiji Katayama

Akio Baba

Yoko Ohkuni

Masao Shimada

A self-assembled film forming composition for forming a phase-separated structure of a block copolymer layer on a substrate, containing a block copolymer and a solvent, and is configured such that: the block copolymer is obtained by bonding a silicon-free polymer to a silicon-containing polymer that contains, as a constituent unit, styrene that is substituted by a silicon-containing group; the silicon-free polymer contains a structure derived from formula [1-1] or formula [1-2]; and the silicon-containing group contains one silicon atom. [In formula [1-1] or formula [1-2], each of Rand Rindependently represents a hydrogen atom, a halogen atom or an alkyl group having 1-10 carbon atoms; and each of R-Rindependently represents a hydrogen atom, a hydroxy group, a halogen atom, an alkyl group having 1-10 carbon atoms, an alkoxy group having 1-10 carbon atoms, a cyano group, an amino group, an amide group or a carbonyl group.]

Composition for forming block copolymer layer for formation of microphase-separated pattern

Provided is a method for producing a liquid medium composition, including using a junction conduit structurehaving a structure in which a first inlet conduitand a second inlet conduitare joined together to form an outlet conduit, and flowing a first liquidcontaining a particular compound into the first inflow conduitand flowing a second liquidcontaining a linking substance into the second inlet conduit, and allowing the flows of the both liquids to join together to mix the both liquids, thus forming a liquid medium compositioncontaining structures formed by the particular compound linked via the linking substance dispersed therein while being flown through the outlet conduit

Method and device for producing liquid culture medium composition

A polymer production method whereby: a flow reactor comprising a flow path wherein a plurality of liquids can be mixed is used; and a monomer is anionically polymerized in the presence of an initiator. The flow reactor comprises a mixer for mixing two liquids, said mixer comprising either a joint member having a double pipe therein or a static mixer member.

Polymer production method

To provide a method whereby a 2-azaadamantane can easily be obtained in good yield. A method for producing a 2-azaadamantane represented by the formula (1), which comprises cyclizing a compound represented by the following formula (2) in the presence of an acid. 

Method for producing 2-azaadamantane

To provide a novel method for producing a 2-azaadamantane compound from a bicyclocarbamate compound. In accordance with the following scheme: a bicyclocarbamate compound represented by the formula (1) is reacted with a halogenating agent to produce a 2-azaadamantane carbamate compound represented by the formula (2), and the 2-azaadamantane carbamate compound is subjected to hydrogenolysis to produce a 2-azaadamantane compound represented by the formula (3) (in the formulae, Ris hydrogen or the like, each of Rand Rwhich are independent of each other, is a hydrogen atom or a Calkyl group, Ar is an aryl group which may be substituted by R, Ris halogen or the like, X is a halogen atom, and Y is X or a hydrogen atom).

Method for producing 2-azaadamantane compound from bicyclocarbamate compound

The invention provides a method for producing 2-azaadamantanes represented by formula (1) in good yields. The method includes cyclizing a compound represented by formula (2) in the presence of an acid. 

There is provided a method for producing a succinimide compound. The method for producing a succinimide compound of formula (3) comprises reacting an aminomalonic ester compound of formula (1) with a compound of formula (2) in a solvent in the presence of a base, wherein an alcohol is used as the solvent and an alkali metal alkoxide is used as the base. (where Rand Rindependently represent an alkyl group having 1 to 12 carbon atom(s) which may be a straight chain, branched or cyclic, etc., Rand Rindependently represent a hydrogen atom, etc., Rrepresents an alkyl group having 1 to 12 carbon atom(s) which may be straight chain, branched or cyclic, etc.).

Method for producing succinimide compound

A method for preparing a 7-quinolynyl-3,5-dihydroxyhept-6-enoate useful as an intermediate for pharmaceuticals, in high yield and in high purity, is presented. It is a method for preparing a 7-quinolinyl-3,5-dihydroxyhept-6-enoate represented by the formula (IV):(wherein R represents an alkyl group or an aryl group), characterized in that a compound represented by the formula (I):(wherein R is as defined above), or a compound represented by the formula (II):(wherein R is as defined above), is reduced by sodium borohydride in the presence of a boron compound represented by the formula (III):R'OBR&#x2033;&#x2003;&#x2003;(III)(wherein R&#x2032; and R&#x2033; represent independently an alkyl group), and then the resultant reaction mixture is treated with an aqueous solution of hydrogen peroxide.

Method for preparing a 7-quinolinyl-3,5-dihydroxyhept-6-enoate

Alcohols are produced in a practical and advantageous method, by the hydrogenation of a carbonyl compound under mild conditions, by reacting the carbonyl compounds with hydrogen in the presence of a bipyridyl derivative, a group VIII transition metal complex, and a base, or by reducing a carbonyl compound in the presence of a bipyridyl derivative, a group VIII transition metal complex, a base, and an alcoholic solvent.

Processes for the preparation of alcohols

Method for optical resolution of piperidine carboxylic acid derivative

The present invention produces novel cis-oxazolidinone compound which is racemic form or optically active form, of a formula (1) ##STR1## wherein R represents C.sub.1 -C.sub.6 alkyl group, C.sub.2 -C.sub.6 alkenyl group, C.sub.1 -C.sub.6 alkoxyl group, C.sub.1 -C.sub.6 alkylamino group, aryl group or halogen atom, and oxazolidinone ring is at cis-configuration, comprising reacting cis-1,2-indene epoxide of a formula (3) ##STR2## form, with sulfonyl isocyanate compound of a formula (4) ##STR3## in the presence of metal halide catalyst. Further, cis-1-amino-2-indanol is produced by hydrolyzing the oxazolidinone compound. The latter compound is useful as an intermediate of HIV-drug.

Oxazolidinone compounds and process for the preparation thereof

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Funabashi, Japan

Masami Kozawa