Yamanouchi Pharmaceutical Company Ltd.

Other

Masaki Yokota

Akihiro Tanaka

Takashi Fujikura

Ryuji Tsuzuki

Takeyuki Yatsu

Yasuo Isomura

Noriaki Nagano

Tetsuya Maeda

Toru Yoden

Ryuichiro Hara

Tokuo Koide

Hideki Anan

Ei-ichi Nakai

Katsuhiko Hamaguchi

Masato Sato

Noriko Nagaoka

Hiroaki Akane

Yasuhito Arakida

Azole derivative with leukotriene (LTs) antagonizing activity and

A compound of the formula (I) or its salt and a process for producing the compounds; The compounds have the effect to dilate neophrovascular tracts; ##STR1## Wherein ##STR2## represents the formula ##STR3## (wherein R.sup.4 is a hydrogen atom or lower alkylsulfonyl); R.sup.1 is hydrogen, lower alkyl, hydroxyl, halogen, amino, or lower acylamino;

Substituted tetrahydroisoquinoline compounds, and process for producing

This invention provides certain novel substituted tetrahydroisoquinoline opticulisomers of the formula: ##STR1## wherein A represents the formula ##STR2## wherein R is hydrogen or halogen; R.sup.1 is hydrogen, lower alkyl, hydroxyl, halogen, amino, or lower acylamino;

A cephalosporin compound represented by the general formula: ##STR1## This compound exhibits a high antimicrobial activity.

Cephalosporin derivatives

This invention provides the single species (-)-(S)-4-(3,4-dihydroxyphenyl)-7, 8-dihydroxy-1,2,3,4-tetrahydroisoquinoline hydrochloride hydrate, which is useful as a nephrovascular dilator.

Substituted 4,5,6,7-tetrahydrothiens[2,3-C]pyridine compounds

A compound of the formula (I) or its salt and a process for producing the compounds. The compounds have the effect of dilating neophrovascular tracts; ##STR1## wherein ##STR2## represents the formula ##STR3## wherein R.sup.4 is a hydrogen atom or lower alkylsulfonyl;

Substituted tetrahydroisoquinoline compounds and method containing them

A compound of the formula (I) or its salt and a process for producing the compounds; The compounds have the effect to dilate neophrovascular tracts; ##STR1## wherein ##STR2## represents the formula ##STR3## (wherein R.sup.4 is a hydrogen atom or lower alkylsulfonyl); R.sup.1 is hydrogen, lower alkyl, hydroxyl, halogen, amino, or lower acylamino;

Production of

Substituted tetrahydroisoquinoline compounds and composition containing

Growing community of inventors

Saitama, Japan

Masaki Yokota