Sharp Corporation

Sharp Kabushiki Kaisha Corporation

Takeda Pharmaceutical Company Limited

Takeda Chemical Industries, Inc.

Sharp Kabushiki Kaishi

Masaki Kawamura

Hiroshi Sakaguchi

Takahisa Yubisui

Keiji Kubo

Fumio Itoh

Hiroki Sakamoto

Takahiko Taniguchi

Hiroshi Banno

Maki Tomoike

Yoshiyuki Fukase

Takanobu Kuroita

Eiji Honda

Shuji Kitamura

Hiroshi Hosono

Mamoru Tobisu

Masaharu Nakayama

Kenji Kondo

A heat exchanger placed in front of an air blower is appropriately supported by a cabinet. In an indoor unit, the heat exchanger is placed only in front of a rotation center of an air-blowing fan. The cabinet includes: an upper left protrusion and an upper right protrusion protruding forward from an upper portion of the cabinet; and a lower left protrusion and a lower right protrusion protruding forward from a lower portion of the cabinet, so that the protrusions support the heat exchanger.

Indoor unit for air conditioner

The present invention relates to a thrombin receptor antagonist containing a compound represented by the formula (I) wherein R, Rand Rare each a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group, or an optionally substituted alkoxy, Ris a group represented by the formula &#x2014;NHCOR, &#x2014;NHSOR, &#x2014;NHCON(R)(R), &#x2014;NHCOORor &#x2014;CONHRwherein R, R, R, R, Rand Rare each a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group and the like), ring A is monocyclic aromatic ring optionally further having substituent(s), Rand Rare optionally bonded to each other to form an optionally substituted nitrogen-containing non-aromatic heterocycle, or a salt thereof or a prodrug thereof. The thrombin receptor antagonist of the present invention has a thrombin receptor (particularly PAR-1) antagonistic action and is useful for the prophylaxis or treatment of PAR-1 mediated pathological condition or disease.

Triazole derivative and use thereof

A thiazoline derivative represented by Formula (I): wherein R is a cyclic hydrocarbon group which may be substituted, or a heterocyclic group which may be substituted; X is a bond or a divalent chain hydrocarbon group which may be substituted; X' is a bond or &#x2014;N(R)&#x2014;; Y is a divalent hydrocarbon group which may be substituted; Y&#x2032; is a bond or &#x2014;C(&#x2550;O)&#x2014;; ring A is a nitrogen-containing heterocycle which may be substituted; Zand Zare each independently a bond or a divalent chain hydrocarbon group which may be substituted; Zis a bond or &#x2014;N(R)&#x2014;; and B is a group represented by the formula: which is useful as a therapeutic drug for thrombosis, is provided.

Thiazoline derivative and use of the same

Novel carbamate derivatives which are useful as drugs because of inhibiting activated blood coagulation factor X and thus exerting an anticoagulant effect. Compounds represented by the formula: wherein Rrepresents a group represented by the formula: (wherein Yrepresents CH&#x2550;CH, etc.), which may be substituted, etc.; the ring A represents an oxo-substituted nitrogen-containing heterocyclic ring which may be further substituted; Rrepresents a hydrogen atom, optionally substituted Calkyl, etc.; Rrepresents optionally substituted Calkyl, etc.; and Z represents an optionally substituted nitrogen containing heterocyclic group, etc., or salts thereof.

Growing community of inventors

Osaka, Japan

Masaki Kawamura