M. Technique Company, Ltd.

M. Techinque Co., Ltd.

Masakazu Enomura

Daisuke Honda

Masaki Maekawa

Kaeko Araki

Jun Kuraki

Kazuya Araki

Kazutaka Takeda

Shiho Aoyagi

Mai Yoshizumi

Hideyuki Oka

Masahito Niikawa

Yasunari Murata

In an agitator in which cavitation arising during treatment of a fluid being treated is suppressed, a stator part S is provided with a plurality of penetration parts in the circumferential direction of the stator part S, and a stator main part positioned between adjacent penetration parts. When a fluid is discharged from the inside of the stator part S to the outside through the penetration part by the rotation of a rotor, in the stator part S for the agitator treating the fluid, the side facing a blade of the rotor is an inner wall surface, the side facing a blade of the rotor is an inner wall surface, the side facing the side opposite to the blade of the rotor is an outer wall surface, an opening of the plurality of penetration parts that is provided in the inner wall surface is an inflow opening, and an opening of the plurality of penetration parts that is provided in the outer wall surface is an outflow opening, the opening area of the inflow opening being larger than the opening are of the outflow opening.

Stirrer

A heat exchanger with which a fluid to be treated or a generated gas can be prevented from stagnating in a heat transfer part, which can be disassembled for good washability, and which can be coated or lined. The heat exchanger is provided with tow flow passages, i.e. a first flow passage and a second flow passage, within a space formed between an inner tube and an outer tube which are concentric to each other. A spiral heat transfer body is disposed between the inner tube and the outer tube, and the spiral heat transfer body has a cross-sectional shape that is substantially triangular in the axial-direction cross section. The space is partitioned into the first flow passage and the second flow passage by the spiral heat transfer body, and heat is exchanged via the spiral heat transfer body between a first fluid flowing within the first flow passage and a fluid flowing within the second flow passage.

Heat exchanger

A heat exchanger includes three flow paths, a first flow path, a second flow path, and a third flow path, which turn spirally in the space formed between an inner cylinder and an outer cylinder are provided. These flow paths are defined by an inner heat transfer body and an outer heat transfer body, and heat exchange is performed through the heat transfer bodies. The heat transfer bodies turn spirally, have a screw shape in an axial cross-sectional view, and are assembled into a screw shape. The flow path area of the first flow path is varied by changing the shapes of a male thread and a female thread, and the second flow path and the third flow path are formed in a spiral shape, allowing for exchange of heat through the heat transfer bodies.

The present application provides a microsphere comprising a lactic acid-glycolic acid copolymer (PLGA) or polylactide (PLA) as a main component, in which a biologically active substance is uniformly dispersed, wherein an average volume-based particle diameter of the microsphere is 1 μm or more and 150 μm or less, and a variation coefficient of area ratios in six regions is 0.35 or less, wherein the area ratios in six regions are calculated by (s/A)×100 (%) wherein the six regions are prepared by preparing a cross section observation sample obtained by cutting the microsphere; observing the cross section observation sample with an electron microscope at a magnification capable of confirming the biologically active substance in the microsphere or a higher magnification; and dividing the electron microscope observation image into six regions; and A is an area of a respective divided region, and s is a sum of cross section areas of the biologically active substance included in the respective divided region. The microsphere of the present invention can appropriately control the initial release amount of the biologically active substance and its release rate during a subsequent release period, and can continuously release the biologically active substance in vivo for a predetermined period of time.

Method of producing a microsphere comprising PLGA or PLA in which a biologically active substance is uniformly dispersed

A vacuum deaerator degasses material to be processed by placing a rotating rotor with a screen in a vacuum vessel, introducing a liquid material to be processed into the rotor from the interior thereof and causing the liquid to pass through the screen to refine the same. The vacuum deaerator is characterized in that: the screen is a cylinder with a circular cross-section and is in the form of a porous plate in which a plurality of through holes are opened in the radial direction of the cylindrical screen; and the screen is provided such that the area of inflow openings is greater than the area of outflow openings, where the inflow openings are openings of a plurality of penetration portions provided on the inner wall face of the screen and the outflow openings are openings of the plurality of penetration portions provided on the outer wall dace of the screen. Thus, the processing capacity of the vacuum deaerator is improved without increasing the size of the device.

Vacuum deaerator

The present invention is a method of producing highly crystalline silver microparticles by a reduction reaction, which comprises precipitating the silver microparticles by reacting a silver solution containing at least silver ions and a reducing agent solution containing at least a reducing agent by a continuous wet reduction method, wherein a reduction rate from the silver solution to the silver microparticles is 99% or more; an average primary particle diameter of the silver microparticles is 100 nm or more and 1,000 nm or less; and an average crystallite diameter relative to the average primary particle diameter of the silver microparticles is 80% or more. Even highly crystalline silver microparticles having 95% or more of the ratio (d/D) of the average crystallite diameter (d) relative to the average primary particle diameter (D), that is, silver microparticles in which almost all silver microparticles are single crystals, can be continuously produced by a liquid phase method, by the present invention.

Method of producing highly crystalline silver microparticles

A fluid treatment device with a new configuration is provided. The fluid treatment device is provided with an upstream treatment unit defined by treatment surfaces that rotate relative to each other, and a downstream treatment unit arranged downstream of the upstream treatment unit. The upstream treatment unit is configured such that, by passing the fluid to be treated into an upstream treatment space defined by the treatment surfaces, the fluid to be treated is subjected to upstream treatment. The downstream treatment unit is provided with a downstream treatment space which performs the function of retaining and mixing the fluid to be treated by means of a labyrinth seal. An upstream outlet of the fluid to be treated from the upstream treatment unit opens into the downstream treatment space, and the downstream treatment space is configured to use the labyrinth seal to perform the function of controlling retention time. The downstream treatment space is provided with narrow seal spaces, and retention spaces arranged upstream of the seal spaces and wider than the seal spaces, and the upstream outlet opens to a retention space.

Fluid processing apparatus

A vacuum deaerator is provided with a refining device with which it is possible to suppress the occurrence of situations involving interrupted discharging and continuously discharge a material being treated that is highly viscous, etc. The vacuum deaerator introduces a liquid material being treated into a vessel having a vacuum therein to perform deaeration and then discharged the material being treated out of the vessel. A rotating rotor with refining device arranged in the vessel and a rotating discharge vane provided separately from the rotating rotor for the purpose of discharging the material being treated in the vessel out of the vessel are installed.

Vacuum deaerator equipped with refining device

The flow reactor includes three flow passages including a first flow passage, a second flow passage, and a third flow passage which spirally circulate within a space formed between an inner tube and an outer tube. The flow passages are compartmented by an inner heat transfer body and an outer heat transfer body. The heat transfer bodies spirally circulate, have a screw-like cross-sectional shape in an axial cross-sectional view, and are assembled in a screw-like configuration. By changing the shapes of a male-thread portion and a female-thread portion, the flow passage area of the first flow passage is changed, the second flow passage and the third flow passage are spirally formed, and heat exchange and reaction take place through the heat transfer bodies.

Flow reactor

The present application provides black perylene pigment microparticles having an average circularity of 0.8 or more which are amorphous; and a method of producing the black perylene pigment microparticles, which comprises a step of mixing a pigment solution in which a black perylene pigment is dissolved and a precipitation solvent for precipitating black perylene pigment microparticles from the pigment solution to form black perylene pigment microparticles, wherein at least one of the pigment solution and the precipitation solvent independently includes a salt of an alkaline earth metal and/or a particle growth inhibitor. The present invention can provide black perylene pigment microparticles having good dispersibility, high concealability and light-shielding property and controlled hue and chroma, and a method of easily producing the same, and the like.

Black perylene pigment microparticles, method of producing the same, black pigment composition comprising the same, and method of producing black perylene pigment microparticles having controlled hue and/or chroma

Provided are a method for producing organic material microparticles and a method for modifying organic material microparticles, whereby it becomes possible to improve the crystallinity of organic material microparticles or achieve the crystal transformation of the organic material microparticles while preventing the growth of the organic material microparticles in a solvent. A surfactant is added to a solvent that is capable of partially dissolving organic material microparticles, and then the organic material microparticles are reacted with the solvent. In this manner, it becomes possible to improve the degree of crystallization of the organic material microparticles or achieve the crystal transformation of the organic material microparticles without substantially altering the particle diameters of the organic material microparticles.

Method for producing organic material microparticles, and method for modifying organic material microparticles

A method of producing an ultraviolet protective agent composition, which has high transparency and excellent protection ability against a light of ultraviolet region of wavelengths of 200 to 420 nm, and an ultraviolet protective agent composition obtained by the production method are provided. The method of producing an ultraviolet protective agent composition includes at least step (a) of precipitating iron oxide microparticles by mixing with a microreactor an iron oxide raw material fluid containing at least Feion, and an iron oxide precipitation fluid containing at least a basic substance; and step (b) of dispersing the above precipitated iron oxide microparticles in a dispersion medium to obtain iron oxide microparticle dispersion, wherein a haze value of the iron oxide microparticle dispersion is 2.0% or less, and a transmittance of the iron oxide microparticle dispersion for the light of the wavelengths of 200 to 420 nm is 2.0% or less.

Method of producing ultraviolet protective agent composition, and ultraviolet protective agent composition obtained thereby

A stirrer is provided that can more efficiently achieve shearing applied, by an action of an intermittent jet flow, to a fluid to be processed. The stirrer concentrically includes a rotor including a blade, a partition wall, and a screen, wherein: the screen includes a plurality of slits in a circumferential direction thereof and screen members located between the adjacent slit; by rotating at least the rotor of the two components, the fluid to be processed is discharged from the inside to the outside of the screen as the intermittent jet flow through the slit of the screen; the screen has a cylindrical shape having a circular cross section; an opening of the slit provided on the inner wall surface of the screen is used as an inflow opening; openings of the plurality of slits provided on the outer wall surface of the screen are used as outflow openings; and the width of the outflow openings in the circumferential direction is set to be smaller than the width of the inflow opening in the circumferential direction.

The present application provides a microsphere in which a main agent is uniformly dispersed in a polymer matrix, wherein an average volume-based particle diameter of the microsphere is 1 &#x3bc;m or more and 150 &#x3bc;m or less, and a variation coefficient of area ratios in four regions is 0.35 or less, wherein the area ratios in four regions are calculated by (s/A)&#xd7;100(%) wherein the four regions are prepared by preparing a cross section observation sample obtained by cutting the microsphere; observing the cross section observation sample with an electron microscope at a magnification capable of confirming the main agent in the microsphere or a higher magnification; and dividing the electron microscope observation image into four regions; and A is an area of a respective divided region, and s is a sum of cross section areas of the main agent included in the respective divided region. The microsphere of the present invention can appropriately control the initial release amount of the main agent and its release rate during a subsequent release period, and can continuously release the main agent for a predetermined period of time.

Main agent uniformly dispersed microsphere and a sustained release formulation comprising the same

A method of producing an organic pigment composition including at least organic pigment microparticles, wherein a diffuse reflectance of the organic pigment microparticles is controlled for the purpose of improving a luminance of a color filter. The luminance of the color filter is controlled to be high, by controlling a ratio of an area of the diffuse reflectance in a target wavelength range to a total area of the diffuse reflectance in the entire measurement wavelength range in a diffuse reflection spectrum of the organic pigment microparticles in the wavelength range of 380 to 780 nm, to be high. The luminance of the color filter is controlled to be high, by coating at least a part of the surface of the organic pigment microparticles with an oxide.

Growing community of inventors

Izumi, Japan

Masakazu Enomura