Sumitomo Chemical Company, Limited

Masaji Hirota

Koji Hagiya

Hajime Ishida

Yoshio Onogawa

Takashi Miyamoto

Hiroyuki Miyazaki

Yuya Yoshimoto

Yuta Nagashima

Masashi Takimoto

Tomonori Yamaoka

Yoko Miyanaga

Yuya Mizushima

Kazuyoshi Yamanaka

Yoko Tagami

Tadayoshi Itoh

The present invention provides a process for producing an isocyanate compound such as 3-methyl-2-methoxymethyl-1-isocyanate benzene and the like. By reacting 3-Methyl-2-methoxymethyl aniline and the like with phosgene in the presence of a tertiary amine at 10&#xb0; C. to 14&#xb0; C. in one or more solvents selected from the group consisting of toluene and xylene, isocyanate compounds such as 3-methyl-2-methoxymethyl-1-isocyanate benzene and the like can be produced at high yield.

Production method for isocyanate compound

By reacting 3-methyl-2-methoxymethylaniline, etc. with a phosgene compound in the presence of a tertiary amine at 10&#xb0; C. to 14&#xb0; C. in at least one kind of solvent selected from a group consisting of chlorobenzene and ortho-dichlorobenzene, an isocyanate compound such as 3-methyl-2-methoxymethyl-1-isocyanatobenzene can be manufactured with good yields.

Isocyanate compound manufacturing method

A new process capable of producing a 2-(aryloxymethyl)benzaldehyde compound is provided. More particularly, a process for producing a 2-(aryloxymethyl)benzaldehyde compound represented by formula (2) comprising a step of hydrolyzing a compound represented by following formula (1); wherein Xand Xeach represent independently a chlorine atom, a bromine atom or an iodine atom, Q, Q, Qand Qeach represent independently a hydrogen atom or a halogen atom, and Ar represents a phenyl group optionally having a substituent.

Method for producing 2-(aryloxymethyl) benzaldehyde compound

A method for producing a phenylacetamide compound represented by formula (1): wherein Q represents a hydrogen atom or a halogen atom, Rrepresents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, Rrepresents an alkyl group having 1 to 4 carbon atoms, Ar represents an unsubstituted or substituted phenyl group, Rrepresents Rwhen Ris a hydrogen atom, and Rrepresents a hydrogen atom when Ris an alkyl group having 1 to 4 carbon atoms; including reacting a phenylacetamide compound represented by formula (2): wherein Q, Rand Ar have the same meanings as defined above; with a dialkyl sulfate represented by formula (3): wherein Rhas the same meaning as defined above;in the presence of a base.

Method for producing phenylacetamide compound

A method of producing a corresponding acetal compound which comprises reacting a benzal halide compound represented by formula (1) (wherein, Q represents a hydrogen atom or a halogen atom, X represents a halogen atom, and Ar represents a phenyl group optionally substituted with at least one group selected from the group consisting of alkyl groups having 1 to 4 carbon atoms and halogen atoms.) and an alcohol compound in the presence of at least one alkaline earth metal compound selected from the group consisting of alkaline earth metal oxides, alkaline earth metal hydroxides and alkaline earth metal carbonates.

Process for production of benzaldehyde compound

A method for producing a compound represented by the following formula (2) (wherein, X, Rand m represent respectively the same meaning as described below)which comprises reacting a compound represented by the following formula (1) (wherein, X represents an optionally substituted alkyl group or the like. Rrepresents an optionally substituted alkyl group or the like. m represents an integer of 0 to 4. When m represents an integer of 2 to 4, Rs may be the same or different from each other)with hydrogen cyanide in an amount of 1.2 to 5 mol with respect to 1 mol of the compound, in the presence of an organic base, in an organic solvent.

Process for production of mandelonitrile compound

Disclosed is a method for producing a compound represented by Formula (4), the method including Step I of adding a solution in which hydrogen chloride is dissolved in an alcohol, to a mixture containing an organic solvent and a compound represented by Formula (1), and Step II of mixing a compound obtained in Step I, represented by Formula (3), with water. 

Method for producing &#x3b1;-hydroxyester compound

Metal catalyst and its use

It is provided to a process for producing adipic acid which comprises making a wastewater containing hydroxycaproic acid and discharged from the step of oxidizing cyclohexane with molecular oxygen in a liquid phase react with hydrogen peroxide in the presence of a tungsten catalyst in the pH range of 0 to 6.

Process for producing adipic acid

A process for producing an epoxide compound, characterized by reacting an olefin compound with hydrogen peroxide in the presence of: a metal oxide catalyst obtained by reacting hydrogen peroxide with at least one member selected from the group consisting of tungsten metal, molybdenum metal, compounds of tungsten and a Group IIIb, IVb, Vb, or VIb element, tungstic acid and salts thereof, compounds of molybdenum and a Group IIIb, IVb, Vb, or VIb element, and molybodic acid and salts thereof; at least one member selected from the group consisting of tertiary amine compounds, tertiary amine oxide compounds, nitrogenous aromatic compounds, and nitrogenous aromatic N-oxide compounds; and a phosphoric acid compound.

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Ibaraki, Japan

Masaji Hirota