Osaka University

National Institutes of Biomedical Innovation, Health and Nutrition

Luxna Biotech Co., Ltd.

Masahito Shimojo

Satoshi Obika

Takao Suzuki

Yuya Kasahara

Masaki Yamagami

Tadashi Umemoto

Disclosed is an oligonucleotide or a pharmacologically acceptable salt thereof, wherein the oligonucleotide comprises at least one defined nucleoside structure, can bind to a human nSR100 gene and has human nSR100 expression inhibiting activity. The oligonucleotide has a length of 12 to 20 mer, and is complementary to a defined target region. Further, disclosed is an nSR100 gene expression inhibitor and a cancer therapeutic agent containing the oligonucleotide or the pharmacologically acceptable salt thereof. The cancer therapeutic agent is used for treatment of small cell lung cancer, prostate cancer, or breast cancer.

Small cell lung cancer therapeutic agent containing oligonucleotide

Growing community of inventors

Osaka, Japan

Masahito Shimojo