Toyo Boseki Kabushiki Kaisha

Toyobo Co., Ltd.

Masahiro Seko

Masakazu Tanaka

Noriko Monden

Hideyuki Yokota

Susumu Arimori

Shigeji Konagaya

Hideto Ohashi

Akito Hamano

The invention provides an antibacterial polymeric molded product containing an anionic compound capable of combining, by ionic bond, with a cationic component of a water-soluble antibacterial agent, wherein the cationic component is combined with the anionic compound by ionic bond at least at the surface of the molded product.

Antibacterial polymeric moldings

Biocompatible polymers

Since an inorganic and/or organic antibacterial agent and a hydrophilic substance are used in combination in this invention to produce an antibacterial composition, the intrinsic antibacterial activity of the inorganic or organic antibacterial agent is markedly increased, so that the antibacterial agent used even in a low concentration shows a high antibacterial activity. High antibacterial moldings can be obtained at a relatively low cost by laminating the antibacterial composition of the invention on an inorganic or organic substrate.

Antibacterial composition and antibacterial laminate

The present invention relates to an organic solvent-soluble mucopolysaccharide consisting of an ionic complex of at least one mucopolysaccharide (preferably heparin or heparin derivative) and a quaternary phosphonium, an antibacterial antithrombogenic composition comprising said organic solvent-soluble mucopolysaccharide and an organic polymer material, an antibacterial antithrombogenic composition comprising said organic solvent-soluble mucopolysaccharide and an antibacterial agent (preferably inorganic antibacterial agent such as silver zeolite), and to a medical material comprising said organic solvent-soluble mucopolysaccharide. The organic solvent-soluble mucopolysaccharide, and the antibacterial antithrombogenic composition and medical material containing the same, of the present invention, can easily impart antithrombogenicity and antibacterial property to a polymer to be a base material, which properties being maintained not only immediately after preparation of the material but also after long-term elution. Thus, the organic solvent-soluble mucopolysaccharide and antibacterial antithrombogenic material of the present invention show superior applicability as a material to impart antithrombogenicity and antibacterial ability to medical materials.

Organic solvent-soluble mucopolysaccharide, antibacterial

Growing community of inventors

Otsu, Japan

Masahiro Seko