Kissei Pharmaceutical Co., Ltd.

Masahiko Uchida

Kenji Yokoyama

Hideki Takeuchi

Kosuke Okazaki

Yuichiro Kai

Hiroaki Kobayashi

Yoshihiro Terao

Norihiko Kikuchi

Harunobu Mukaiyama

Hiroaki Shiohara

Yuji Hoyano

Hiromu Harada

Akira Iyobe

Ritsu Suzuki

Arao Ujiie

Koji Kamata

The present invention relates to a 5-amidino-2-hydroxybenzenesulfonamide derivative represented by the general formula: 

5-amidino-2-hydroxybenzenesulfonamide derivatives, pharmaceutical compositions containing the same and intermediates for their preparation

The present invention relates to a 5-amidino-2-hydroxybenzenesulfonamide derivative represented by the general formula: wherein Ris a hydrogen atom or an optionally substituted lower alkyl group;

The present invention relates to a 5-amidino-N-(2-aminophenethyl)-2-hydroxybenzenesulfonamide derivative represented by the general formula:wherein Ris a hydrogen atom or a lower alkyl group;

5-amidino-n-(2-aminophenethyl)-n-hydroxy-benzenesulffonamide derivative, medical composition containing the same, pharmaceutical use thereof and intermediate therefor

Piperidino-3,4-dihydrocarbostyril compounds represented by the formula: ##STR1## wherein R.sup.1 represents a hydroxy group or an acyloxy group having 2 to 11 carbon atoms; one of R.sup.2 and R.sup.3 represents a nitro group, a cyano group, an alkoxycarbonyl group having 2 to 7 carbon atoms, an alkyl group having 1 to 4 carbon atoms, a haloalkyl group having 1 to 3 carbons atoms, or a halogen atom, and the other represents a hydrogen atom; and pharmaceutically acceptable salts thereof, exhibit platelet aggregation inhibiting activity and thus being useful as therapeutic agents for the prevention or treatment of cerebral ischemic disorders and arterial ischemic disorders.

Piperidino-3,4-dihydrocarbostyril compounds

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Nagano, Japan

Masahiko Uchida