Hitachi-high-technologies Corporation

Hitachi High-tech Corporation

Hitachi-science Systems, Ltd.

Roche Diagnostics Operations, Inc.

Hitachi, Ltd.

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Masaharu Nishida

Isao Yamazaki

Hideto Tamezane

Masaaki Hanawa

Kumiko Kamihara

Hitoshi Otake

Katsuaki Takahashi

Yoko Inoue

Tomonori Mimura

Hiroshi Ohga

Hitoshi Ohtake

Kenichi Yagi

Masafumi Shimada

Osamu Matsumoto

Hirofumi Sasaki

Hiroshi Mitsumaki

Takeshi Sato

Masaki Shiba

Stephan Sattler

Ryo Miyake

Hitoshi Tokieda

Takao Terayama

Yoshihiro Nagaoka

Takeshi Shibuya

Tetsuji Kawahara

Tatsuya Fukugaki

Yoshimitsu Takagi

Shinji Azuma

Heino Eikmeier

Tetsuya Isobe

Hideyuki Yanami

Ryota Kamoshida

Dietmar Kappelhoff

Takashi Nakasawa

Atsushi Suzuki

Sayaka Sarwar

Yoshiaki Igarashi

Qing Li

Andrew McCaughey

Naohiko Fukaya

Sayaka Asada

Christoph Möllers

Takehiro Fujita

Andrew Mccaughey

Provided are a program and personal information protection method which are executed by a system which is operated by a medical practitioner, said program and method comprising: a display process of causing a monitor partto display an examination result screenincluding personal information which identifies a subject; an identification process of identifying the personal information in the examination result screenwhich is displayed in the display process; and an invalidation process of invalidating the personal information identified in the identification process in a captured image which includes the examination result screen. Instances of personal information being displayed in error to outside users are thus reduced in comparison to the prior art, and sharing of examination result information is implemented smoothly.

Display device, information terminal, personal information protection method, program, and recording medium whereon program is recorded

The automatic analyzer includes: a liquid dispensing mechanism that performs suction of a liquid; a pressure sensor that measures a change of an internal pressure of a probe provided at the liquid dispensing mechanism; a determination section that determines whether the suction of the liquid by the probe is normal suction or air suction abnormality; an analysis section; a storage section that stores a cumulative number of times of air suction abnormality per liquid and an allowable cumulative number for the cumulative number of times of air suction abnormality; and a controller that exercises operation control over the liquid dispensing mechanism, the determination section, and the analysis section. The controller exercises control such that the cumulative number of times of air suction abnormality is updated and the updated cumulative number is stored in the storage section even if the air suction abnormality occurs non-consecutively.

Automatic analyzer

The present invention relates to an improved abnormality determining method for an automatic analyzer and related automatic analyzer that detects abnormalities for a reaction process of a reaction solution. The method for determining the presence of absence of abnormalities in the reaction process and performs the determination by acquiring acquisition conditions for multiple items of measured data, acquiring the measured data detected by a spectral detector that match the acquisition conditions, calculating a feature quantity of the measured data, generating a determination criterion based on the feature quantity, and determining the presence or absence of abnormalities by comparing the feature quantity of the measured data subject to the determination with the determination criterion. The acquisition condition includes information relating to a number of a divisions of a measured value range and information relating to the number of items of data in each divided segment.

Abnormality determining method, and automatic analyzer

The automatic analyzer includes a storage unit storing the reaction containers of cleaning target by day unit in such a manner that all the reaction containers mounted on a reaction disk are to be cleaning target within a plurality of days, and a control unit exerts a control in such a manner that during an operation state after the sample of analysis object is dispensed to the reaction containers, a sample of analysis object in each of the reaction containers is analyzed, and not the sample but a detergent is dispensed to the reaction containers of cleaning target of an appointed day, the reaction containers of cleaning target of the appointed day being stored in the storage unit, to soak and wash the reaction containers for a certain time.

The purpose of the present invention is to provide an automatic analysis device capable of determining, through a simple processing, whether or not idle aspirate has occurred. The automatic analysis device according to the present invention determines whether or not idle aspirate has occurred, by calculating a parameter which specifies whether or not the length of a portion of a path through which the sample passes inside a dispensing probe is shorter than that during normal aspirate, the portion being actually filled with a sample (see FIG.).

Automatic analysis device

An automatic analyzer which is capable of detecting a dispensing abnormality with a high degree of accuracy without causing the decrease in the determination performance or the increase in the calculation amount caused by the configuration balance of the reference database is implemented. A dispensing nozzle of a sample dispensing mechanismis immersed in a dispensing target contained in a specimen containerand sucks the dispensing target, and internal pressure of the dispensing nozzle of the sample dispensing mechanismof ejecting the sucked dispensing target to a reaction containeris detected through a pressure sensor. A plurality of feature quantities are extracted from a waveform of the detected pressure, and a determination result is output through a linear combination formula using an optimal coefficient for a determination function that receives a plurality of feature quantities and outputs one value. The determination result indicates whether or not dispensing of the sample dispensing mechanismis performed normally in accordance with the magnitude of the output result of the determination function.

A reagent container transfer mechanism transfers a reagent container selected from among reagent containers stored in a second reagent container storage section to a first reagent container storage section. A controller controls the reagent container transfer mechanism to transfer a reagent container from a second reagent container storage section to the first reagent container storage section on the basis of a predetermined priority condition. The predetermined priority condition is one of a reagent provided with an effective calibration curve result, a number of remaining tests, and an expiration date of a reagent.

A pressure signal process unit acquires data under a predetermined condition and a statistic distance between the acquired data and determination-purpose reference data stored in a storage unit is calculated. It is determined whether or not dispensing is abnormal and whether the determination-purpose reference data is suitable for an abnormality detection function to be properly fulfilled. If the determination-purpose reference data is not suitable for an abnormality detection function to be properly fulfilled, temporary determination-purpose reference data is prepared so as to be compared with the previously acquired data under a predetermined condition. If a difference therebetween is greater than a predetermined threshold value, a possibility that an automatic analyzer may have an abnormal component or that a failure may occur in the automatic analyzer is determined, and the result is transmitted to cause a display device to display an alarm.

An automatic analyzer that accurately detects dispensation abnormality in dispensation conditions with small suction quantities has a statistical distance calculation unit that calculates characteristic variables regarding a sucking operation in the first dispensation and calculates a statistical distance D from reference data to the characteristic variables extracted from a memory. A comparison unit compares the statistical distance D with a preset threshold value stored in memory and if the statistical distance D is less than the preset threshold value, the first discharging operation is performed. A controller judges whether a single-handed judgment based on a dispensation quantity condition of the second or subsequent dispensation is possible or not. If the single-handed judgment is impossible, reference data is selected based on a judgment quantity regarding the first dispensation. Whether the sucking operation in the second or subsequent dispensation is normal or abnormal is judged based on the selected reference data.

The dispensing mechanisms dips a dispensing nozzle in a dispensing target contained in a container, and, aspirates the dispensing target, and discharges the dispensing target to a reaction container. One item of determination-purpose reference data is selected from multiple items of the determination-purpose reference data which is stored in a storage unitand used in determining whether or not the dispensing mechanisms, andare abnormal, based on the detection result from a pressure sensorwhen the dispensing mechanisms, anddispense a reference dispensing target configured to contain a known ingredient; and whether or not the dispensing mechanisms, andare abnormal is determined, based on the detection result from the pressure sensorand the selected determination-purpose reference data when the dispensing mechanisms, anddispense a dispensing target used in analysis.

A plunger is moved downwardly in predetermined distance while the tip of the sample probe is immersed in a sample to suck the sample into the probe. A pressure sensor detects the pressure fluctuation during the suction operation, an AD converter converting the signals into digital signals to send the signals for a signal processing unit. The signal processing unit extracts feature variables data of a suction waveform to calculate the Statistical distance from normal group data. The Statistical distance an a threshold value are compared with each other, it is judged that there is an abnormality in the suction operation when the Statistical distance is more than or equal to the threshold value. When the Statistical distance is smaller than the threshold value, an operation is proceeded to a discharge operation.

The automatic analyzer includes: a first reagent container storage section storing a plurality of reagent containers; a regent dispensing mechanism for dispensing a reagent from a reagent container stored in the first reagent container storage section; a second reagent container storage section storing a plurality of reagent containers; a reagent container transfer mechanism for transferring a reagent container selected from among reagent containers stored in the second reagent container storage section to the first reagent container storage section; and a controller configured to control the reagent container transfer mechanism to transfer a reagent container from the second reagent container storage section to the first reagent container storage section on the basis of a predetermined priority condition. The predetermined priority condition is one of a reagent provided with an effective calibration curve result, a number of remaining tests, and an expiration date of a reagent.

Reagent transfer device

In a clinical laboratory, the degree of contamination of an automatic analyzer may constantly change due, for instance, to the operation of the automatic analyzer and newly added examinations, and there is a risk of failure to adequately maintain the performance of the automatic analyzer by performing calibration at conventional intervals. Meanwhile, the result of quality control varies depending on the performance of an unsealed reagent. Hence, performing calibration at predetermined intervals may fail to flexibly calibrate the reagent when the performance of the reagent is changed by reagent replenishment or by contamination. Provided is a quality control method for issuing a warning to indicate an optimum calibration method and calibration intervals in accordance with the contents of a quality control screen and with the pattern of variation in the result of calibration.

Quality control system

An automatic analyzer which performs a suction operation a plurality of times on a same sample has a sample dispensing unit, a liquid level sensor which detects the liquid level of the sample in a sample vessel, an arithmetic unitwhich computes a liquid level height hat the end of a first suction operation of the two consecutive suction operations from a liquid level height hand a sample suction volume Vdetected at the start of the first suction operation, a storage unitwhich stores the liquid level height hcomputed by the arithmetic unit, and a determination unitwhich compares a liquid level height hdetected at the start of a second suction operation following the first suction operation with the liquid level height hat the end of the first suction operation.

Automatic analyzer and method for determining malfunction thereof

Growing community of inventors

Hitachinaka, Japan

Masaharu Nishida