Nippon Shokubai Co., Ltd.

Foundation for Biomedical Research and Innovation at Kobe

Ii, Masaaki

Masaaki Ii

Yasuhiko Tabata

Tomomi Makino

Takuma Nakada

To provide a spheroid-containing cell preparation exhibiting a high therapeutic effect for a cartilage tissue-related disorder as a treatment target. A prophylactic or therapeutic agent for a cartilage tissue-related disorder contains, as an effective ingredient, a spheroid including cultured mesenchymal stem cells.

Cell preparation for treating cartilage tissue-related disorder

A preparation containing a statin-encapsulated nanoparticle obtained by encapsulating statin in a nanoparticle containing a bioabsorbable polymer is disclosed. The nanoparticle has a number average particle diameter of less than 1000 nm. The preparation is used to enhance the function of a stem cell. A stem cell with an enhanced function is disclosed. The stem cell takes up and contains the statin-encapsulated nanoparticle.

Statin-encapsulated nanoparticle preparation for enhancing stem cell function, stem cell with enhanced function containing statin-encapsulated nanoparticle, and method for producing same

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Osaka, Japan

Masaaki Ii