Apitope Technology (bristol) Limited

Apitope Technology Limited

Mary Ponsford

David Wraith

Heather Streeter

Graziella Mazza

David Cameron Wraith

Heather Barbara Streeter

David Cameron University Of Bristol Wraith

Heather Barbara University Of Bristol Streeter

Stephen Mark University Of Edinburgh Anderton

Graziella University Of Bristol Mazza

There is provided a peptide that is capable of binding to an MHC class I or II molecule without further processing (i.e., an apitope), which comprises a portion of the region 131-158 of myelin basic protein. In particular, there is provided an apitope which is selected from the following myelin basic protein peptides: 134-148, 135-149, 136-150, 137-151, 138-152, 139-153, 140-154. There is also provided the use of such a peptide in a pharmaceutical composition and a method to treat and/or prevent a disease using such a peptide.

Tolerogenic peptides from myelin basic protein

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Bristol, United Kingdom

Mary Ponsford