Chiron Corporation

Albert Einstein College of Medicine

Cetus Oncology Corporation

Mary Kim Warren

Leah B Conroy

Robert Drummund

Peter Ralph

Alice M Wang

Ernest S Kawasaki

Martha B Ladner

Mazie Yee Coyne

James E Strickler

Janelle N Van Arsdell

Judit Csejtey

Albert Boosman

E Richard Stanley

Kenneth J Wilson

Described herein are compositions that have prophylactic or therapeutic applications for disease resulting from the production of cytokines, and preferably the cytokine IL-6, wherein the compositions consist of activin like molecules.

Inhibitor of cytokine activity and applications thereof

The present invention relates to the purification of proteins, to the products of such purification, and to DNA probes constructed therefrom. More specifically, the invention relates to the purification and sequencing of murine and human colony stimulating factor-1 (CSF-1).

Purified human CSF-1

A colony stimulating factor. CSF-1, is a lymphokine useful in overcoming the immunosuppression induced by chemotherapy or resulting from other causes. CSF-1 is obtained in usable amounts by recombinant methods, including cloning and expression of the murine and human DNA sequences encoding this protein.

Recombinant colony stimulating factor-1

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Rockville, MD, United States of America

Mary Kim Warren