Carnegie Institution of Washington

University of Massachusetts

Other

Mary K Montgomery

Craig C Mello

SiQun Xu

Andrew Fire

Hiroaki Tabara

Samuel E Driver

Lisa Timmons

Stephen A Kostas

Kim Shearrow

Crag C Mello

A process is provided of introducing an RNA into a living cell to inhibit gene expression of a target gene in that cell. The process may be practiced ex vivo or in vivo. The RNA has a region with double-stranded structure. Inhibition is sequence-specific in that the nucleotide sequences of the duplex region of the RNA and of a portion of the target gene are identical. The present invention is distinguished from prior art interference in gene expression by antisense or triple-strand methods.

Genetic inhibition by double-stranded RNA

Genetic inhibition of double-stranded RNA

A portable and stowable quilting wall has generally rectangular body composed of a smooth backing sheet sewn peripherally to a mating front sheet of heavy nap felt. A top hem mounts spaced pieces of hook fasteners interspersed with holes. A bottom hem confines a heavy rod, while the backing sheet mounts strips of loop fasteners that are spaced to engage the hook fasteners when the wall is rolled up on itself to retain the quilting wall in a rolled-up condition for easy movement and storage. The felt nap releasably engages pieces of quilt pieces placed and retains them in both rolled-up and unrolled conditions, without the use of added adhesive or mechanical fasteners. The holes in the top hem receive hooks to hang the unrolled sheet against a wall or door, while the rod maintains the quilting wall flat against a vertical surface.

Portable and stowable quilting design wall

Growing community of inventors

Washington, DC, United States of America

Mary K Montgomery